Tolerance of MRSA ST239-TW to chlorhexidine-based decolonization; evidence for keratinocyte invasion as a mechanism of biocide evasion

Over the past 20 years there have been two dominant pandemic healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) clones in the UK, EMRSA –15 (ST22) and EMRSA-16 (ST36), with lower prevalence of other clones (ST8, ST239, ST5 and ST247). HA-MRSA rates have decreased significantly since the mid-2000’s 1–4 following the introduction of a comprehensive UK-wide infection control program comprising re-enforcement of basic infection co ntrol practices and targeted measures of screening, contact precautions, patient isolation and decolonization.

Source: Journal of Infection - October 24, 2018 Category: Infectious Diseases Authors: Helene Marbach, Gema Vizcay-Barrena, Kaveh Memarzadeh, Jonathan A. Otter, Smriti Pathak, Robert P. Allaker, Richard D. Harvey, Jonathan D. Edgeworth Source Type: research