Non-invasive brain stimulation in the modulation of cerebral blood flow after stroke: a systematic review of Transcranial Doppler studies

NIBS has been successfully explored as a biomarker and therapeutic adjunct for functional recovery after stroke. rTMS and tDCS are two such promising neuromodulatory techniques that have been widely investigated to prime the motor areas of the brain in combination with task-specific practice (Bastani et al., 2012, Hsu et al., 2012, Jodie et al., 2015, Le et al., 2014). Although these techniques have demonstrated modest efficacy, clinical translation is still limited as the underlying physiological mechanisms are not completely understood, nor is the inter-individual variability associated with these techniques resolved (L ópez-Alonso et al., 2014, Maeda et al., 2000, Wiethoff et al., 2014).
Source: Clinical Neurophysiology - Category: Neuroscience Authors: Source Type: research

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Publication date: Available online 9 December 2019Source: Annals of Physical and Rehabilitation MedicineAuthor(s): I Laffont, J Froger, C Jourdan, K Bakhti, LEH Van Dokkum, A Gouaich, HY Bonnin, P Armingaud, A Jaussent, MC Picot, E Le Bars, A Dupeyron, C Arquizan, A Gelis, D MottetAbstractBackground. Few rehabilitation methods have proven their efficacy in increasing sensori-motor recovery and/or function of the upper limb (UL) after stroke. Video games (VGs) are promising tools in this indication.Objective. To compare UL rehabilitation by using VGs and conventional rehabilitation (CR) in patients with sub-acute stroke.Des...
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
Publication date: Available online 9 December 2019Source: NeuropsychologiaAuthor(s): Fang Wang, Urs MaurerAbstractHow and when top-down information modulates visual-orthographic processing is an essential question in reading research. In a previous study, we showed that task modulation of print-tuning started at around 170 ms after stimulus presentation in the N1 offset of the ERP, while the N1 onset was yet unaffected. Here we test how prior category-level expectation affects visual-orthographic processing. Familiar, left/right-structured Chinese characters and stroke number matched, unfamiliar Korean characters were pr...
Source: Neuropsychologia - Category: Neurology Source Type: research
Condition:   Stroke Intervention:   Other: Observational study Sponsors:   Parc de Salut Mar;   Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta Not yet recruiting
Source: - Category: Research Source Type: clinical trials
What are the current trends and hot topics in neurology? The increasing insights into the genetics and molecular bases of neurological disorders open new perspectives for specific and personalized treatments. This is evidenced most dramatically by the antisense therapy for spinal muscular atrophy. Promising neurological research currently targets neurodegenerative diseases such as amyotrophic lateral sclerosis, Parkinson’s disease, Duchenne muscular atrophy, or Huntington’s disease. Likewise, brain-machine interfaces and neuroprosthetics offer huge potential. Never before has it been more important and more exc...
Source: BioMed Central Blog - Category: General Medicine Authors: Tags: Uncategorized Source Type: blogs
We report a young man presenting recurrent ischemic strokes with selective finger weakness in whom serial motor cortex mapping procedures were performed.ResultFollowing the first stroke, which largely spared the motor cortex, motor mapping displayed overlap of the motor representations of the hand muscles. The second focal stroke, affecting the lateral part of the hand knob, resulted in selective loss of the first dorsal interosseous muscle motor evoked potentials while sparing those of the adductor digiti minimi muscle. This observation is in apparent contradiction with the first mapping results that suggested complete ov...
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
(University of Southern California) A new nanoparticle innovation that detects unstable calcifications that can trigger heart attacks and strokes may allow doctors to pinpoint when plaque on the walls of blood vessels becomes dangerous.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
(University of Georgia) Taking a baby aspirin every day to prevent a heart attack or stroke should no longer be recommended to patients who haven't already experienced one of these events.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
AbstractPurpose of reviewThe goal of this paper is to provide the reader with a review of the evidence supporting the surgical and medical management of patients with asymptomatic internal carotid artery (ICA) stenosis.Recent findingsBased on the results of earlier clinical trials, surgical intervention with carotid endarterectomy (CEA) has long been the preferred method of management for patients with asymptomatic severe carotid stenosis. Carotid artery stenting (CAS) is another less invasive surgical option that has similar outcomes over the long-term. However, more recent improvements in medical management have reduced ...
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research
This study proposes a multi-center RCT in order to compare outcomes of warmer hypothermic strategies during aortic hemiarch surgery on a composite endpoint of neurologic and acute kidney injury (AKI).Methods/designThis is a prospective multi-center, single-blind two-arm RCT comparing mild (32  °C) versus moderate (26 °C) hypothermic cardiac arrest in patients (n = 282) undergoing hemiarch surgery with antegrade cerebral perfusion (ACP). The primary endpoint is a composite of neurological injury (incidence of transient ischemic attack and/or stroke) and Kidney Disease Improving Global Out...
Source: Trials - Category: Research Source Type: clinical trials
Source: Journal of Neurology - Category: Neurology Source Type: research
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