Quantification of permethrin resistance and < i > kdr < /i > alleles in Florida strains of < i > Aedes aegypti < /i > (L.) and < i > Aedes albopictus < /i > (Skuse)

by Alden S. Estep, Neil D. Sanscrainte, Christy M. Waits, Sarah J. Bernard, Aaron M. Lloyd, Keira J. Lucas, Eva A. Buckner, Rajeev Vaidyanathan, Rachel Morreale, Lisa A. Conti, James J. Becnel Recent outbreaks of locally transmitted dengue and Zika viruses in Florida have placed more emphasis on integrated vector management plans forAedes aegypti (L.) andAedes albopictus Skuse. Adulticiding, primarily with pyrethroids, is often employed for the immediate control of potentially arbovirus-infected mosquitoes during outbreak situations. While pyrethroid resistance is common inAe.aegypti worldwide and testing is recommended by CDC and WHO, resistance to this class of products has not been widely examined or quantified in Florida. To address this information gap, we performed the first study to quantify both pyrethroid resistance and genetic markers of pyrethroid resistance inAe.aegypti andAe.albopictus strains in Florida. Using direct topical application to measure intrinsic toxicity, we examined 21Ae.aegypti strains from 9 counties and found permethrin resistance (resistance ratio (RR) = 6-61-fold) in all strains when compared to the susceptible ORL1952 control strain. Permethrin resistance in five strains ofAe.albopictus was very low (RR
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research