Targeting Upstream Kinases of STAT3 in Human Medulloblastoma cells.

CONCLUSION: Our results suggest that the small molecule inhibitors of STAT3 upstream kinases, ruxolitinib, tofactinib, KX2-391, and dasatinib could be novel and attractive candidate drugs for the treatments of human medulloblastoma. PMID: 30332965 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30332965?dopt=Abstract

Source: Current Cancer Drug Targets - October 16, 2018 Category: Cancer & Oncology Authors: Wei J, Ma L, Li C, Pierson CR, Finlay JL, Lin J Tags: Curr Cancer Drug Targets Source Type: research