What Do Measles, Tuberculosis, and Grains Have in Common?
What do measles, tuberculosis, and grains have in common? For that matter, what do anthrax, influenza, and brucellosis also share in common with grains? All the conditions listed are examples of zoonoses, i.e., diseases contracted by humans from animals. When humans first invited domesticated grazing creatures–cows, sheep, goats–into our huts, adobe homes, or caves, often sleeping in the same room, using them for milk or food, we acquired many of their diseases. These diseases were unknown prior to the human domestication of grazing ruminants. The process of animal domestication changed the course of human civilization, providing a source of calories from their meat and organs, products made from the milk from their mammary glands, and led to the practices of fermentation, cheesemaking, and putting animals to work as beasts of burden. In parallel, we acquired a long list of zoonoses from the same animals, such as the massive epidemic of tuberculosis that has plagued humans. Grazing ruminants graze on grasses. Curiously, the human consumption of the seeds of grasses–i.e., “grains”–coincides with the domestication of grass-grazing ruminants. It is therefore tempting to speculate that the period of global climate change (increased temperature and dryness) recorded by geologists that caused a shortage of food for humans approximately 9000-12.000 years ago provided the motivation for hungry, desperate humans to observe the eating behavior ...
Publication date: Available online 17 September 2019Source: Reumatología Clínica (English Edition)Author(s): Carola Baliu-Piqué, Elena Nogués-Antich, Marta Cucurell-Palomas, Dolors Grados
ConclusionsStudents view college as an appropriate time to develop food literacy and the university as a trusted partner. However, efforts to promote food literacy should acknowledge perceived challenges and varying motivations for engaging with food.
In this study, we investigated the ability of raspberry fruit extract (RBE) to mitigate adipose tissue dysfunction using hypertrophied 3T3-L1 adipocytes. The obtained results showed that RBE decreased intracellular ROS generation in hypertrophied adipocytes by enhancing expression of antioxidant defense enzymes SOD, catalase, and GPx, and inhibiting an oxidant enzyme NADPH oxidase 4. Moreover, RBE reduced lipid accumulation accompanied by increased lipid mobilization. RBE significantly inhibited LPL, aP2, FAS and PLIN mRNA expression, and enhanced the expression of HSL. Furthermore, RBE exhibited a high anti-inflammatory p...
This study was aimed to examine the effect of apple phlorizin on lipid accumulation in HepG2 cell and hamsters (Thirty-six male Golden Syrian hamsters) fed with atherogenic diet. Dietary supplementation of 0.9% phlorizin significantly decreased the level of plasma total cholesterol (TC), triacylglycerols (TG), activity of cholesteryl ester transfer protein (CETP) and liver 3-hydroxy-3-methyl glutaryl coenzyme A reductase (HMG-CoA-R), alongside down-regulated the gene expressions of intestinal Niemann-Pick C1-like 1 (NPC1L1), HMG-CoA-R and up-regulated ATP-binding cassette transporters subfamily G members 5/8 (ABCG5/8) gene...
Conclusions/Implications for Practice Sleep quality in Chinese nurses is influenced directly and indirectly by various modifiable work-related factors. Interventions such as adjusting work shifts and reducing job burdens should be prioritized by administrative staff to ensure the sleep quality and clinical performance of Chinese nurses and to subsequently improve nursing care quality.
Conclusions: These environment-related barriers may be resolved through changes in the behavior of children, parents, and teachers as well as through the continued efforts of schools, community stakeholders, and policymakers, all of whose cooperation is essential to fostering a healthy food environment for children.
An outbreak of a vaping-related illness in the United States has sickened hundreds, and an epidemic of youth vaping there has been called a "public health crisis." In the UK, e-cigarettes have been embraced mostly as an effective way for adults to quit combustible cigarettes.
ConclusionsEmotion dysregulation is associated with symptoms of depression and anxiety in PwMS. Given the malleability of this construct, this study underscores the importance of further investigating emotion dysregulation, and possibly adopting it as a surrogate endpoint in interventions targeting affective disorders in PwMS.
ConclusionsThe immuno-regulatory functions of B cells were significantly impaired whereas TFH cells were markedly increased in the acute phase of MOG-antibody-associated demyelination. Despite having distinct clinical features, MOG-antibody-associated demyelination shared a similar lymphocytic profile with AQP4-antibody-positive NMOSD in the acute relapse phase.
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