Feasibility of extracellular volume quantification using dual-energy CT

ObjectiveTo assess the feasibility of dual energy CT (DECT) to derive myocardial extracellular volume (ECV) and detect myocardial ECV differences without a non-contrast acquisition, compared to single energy CT (SECT).MethodsSubjects (n  = 35) with focal fibrosis (n = 17), diffuse fibrosis (n = 10), and controls (n = 9) underwent non-contrast and delayed acquisitions to calculate SECT-ECV. DECT-ECV was calculated using the delayed acquisition and the derived virtual non-contrast images. In the control and diffuse fi brotic groups, the entire myocardium of the left ventricle was used to calculate ECV.

Source: Journal of Cardiovascular Computed Tomography - October 20, 2018 Category: Radiology Authors: Marly van Assen, Carlo N. De Cecco, Pooyan Sahbaee, Marwen Eid, Parkwood Griffith, Maximillian J. Bauer, Rock Savage, Akos Varga-Szemes, Matthijs Oudkerk, Rozemarijn Vliegenthart, U. Joseph Schoepf Source Type: research