Histone deacetylase inhibitors sensitize 5-fluorouracil-resistant MDA-MB-468 breast cancer cells to 5-fluorouracil.

In conclusion, the results of the present study revealed that HDAC inhibitors increase the sensitivity to 5-FU in 5-FU-sensitive and -resistant cells. PMID: 30333885 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/30333885?dopt=Abstract

Source: Oncology Letters - October 21, 2018 Category: Cancer & Oncology Tags: Oncol Lett Source Type: research