Does Hyoscine improve polyp detection rate during colonoscopy?Systematic Review & Meta-analysis of randomized clinical trials

Conclusion; This meta-analysis found no significant impact of Hyoscine on polyp and adenoma detection when used during colonoscopy.
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research

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The sequence of events leading to the development of colorectal cancer, currently the third most common malignancy in Western countries, is effectively disrupted by the resection of its precursor lesions. Colonoscopy is the mainstay in lesion detection, and endoscopic polypectomy is the conventional therapeutic response for the overwhelming majority of identified polyps. Approximately 2% of lesions are larger (>20  mm) and are laterally spreading lesions (LSLs). EMR is considered the standard of care for the majority of these because it has been proved to be safer, less resource-intensive, and less expensive than surgery.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
Authors: Tanaka Y, Inoue T, Kakimoto K, Nakazawa K, Tawa H, Hirata Y, Okada T, Nouda S, Kawakami K, Takeuchi T, Egashira Y, Higuchi K Abstract Linked color imaging (LCI) is a novel endoscopic system used to increase color contrast. As LCI does not decrease luminal brightness, it may improve the detection of colonic neoplasms. However, the extent to which LCI improves the visibility of colonic polyps has not yet been determined. Between December 2016 and May 2017, patients who received total colonoscopy were consecutively recruited into this retrospective, single-center study. For each polyp identified, images obtai...
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
Medtronic is taking some very big steps with artificial intelligence. The Dublin-based company is launching GI Genius – a system it said is the first to use AI to detect colorectal polyps. The product’s launch is taking place during United European Gastroenterology Week in Barcelona, Spain. GI Genius was developed by Cosmo Pharmaceuticals and has CE mark. Medtronic is bringing the solution to the market through a distribution agreement with the Dublin-based Cosmo Pharmaceuticals. The GI Genius module uses advanced artificial intelligence to highlight the presence of pre-cancerous lesions...
Source: MDDI - Category: Medical Devices Authors: Tags: Digital Health Source Type: news
Conclusions: We suggested that GB polyps are associated with proximal colon polyps. Colonoscopy may be a more effective strategy for screening proximal precancerous lesions among patients with GB polyps. The association between GB disease and colon polyps demands further prospective investigation. PMID: 31611916 [PubMed]
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
Abstract Background/Aims: We evaluated the miss rates of polyps, adenomas, and advanced neoplasia of polypectomy-referring hospitals and risk factors for missed adenomas. Methods: We compared medical records and electronic images of initial colonoscopies from polypectomy-referring hospitals with those of corresponding therapeutic colonoscopies from Seoul St. Mary's Hospital obtained from May 2014 to February 2016. Results: A total of 147 patients (56.6 ± 12.1 years, 37 females) were included. The mean number of polyps and adenomas detected on initial colonoscopy was 2.4 ± 1.7 and 1.7 &plusm...
Source: The Korean Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Korean J Intern Med Source Type: research
Incomplete resection of colorectal neoplasia decreases colonoscopy efficacy. Conventional resection (CR) of polyps, performed in a gas-distended colon, is the current standard, but incomplete resection rates of approximately 2% to 30% for nondiminutive (>5 mm), nonpedunculated lesions are reported. Underwater resection (UR) is a novel technique. The aim of this study was to determine the incomplete resection rates of colorectal lesions removed by UR versus CR.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Source Type: research
Conditions:   Artificial Intelligence;   Colonoscopy Intervention:   Device: Artificial intelligence assisted colonoscopy Sponsor:   Side Liu Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion Endocuff-assisted colonoscopy reduces the duration of polypectomy, which may be due to a more stable scope position during resection. Further studies are needed to investigate whether comparable effects will be seen for other interventions, such as clipping or biopsy sampling. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
A seventeen-year-old male patient underwent surveillance colonoscopy 7 years after being diagnosed with ulcerative colitis. The procedure revealed a 2-cm pedunculated polyp in the transverse colon (Fig. 1A) and superficial ulcerations at the hepatic flexure. Histologic evaluation demonstrated a colonic polyp with branching smooth muscle fibers without significant increased lamina propria-to-crypt ratio, crypt dilatation, or dysplasia (Fig. 1B, H&E, ÿ40). Smooth-muscle actin immunostain highlighted the smooth muscle bands (figure C, ÿ40).
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Image of the Month Source Type: research
Colon polyp surveillance now accounts for 25% of all colonoscopies performed. The evidence that colonoscopy surveillance reduces colorectal cancer (CRC) incidence or mortality is weak. The biology of the baseline lesions and quality of the baseline exam are two primary factors contributing to post-colonoscopy CRC. Prior recommendations for surveillance were based largely on the likelihood that patients with adenomas would develop advanced adenomas, a surrogate for CRC. There is now evidence that baseline colonoscopy findings are strongly associated with the risk of incidence or death from CRC.
Source: Gastroenterology - Category: Gastroenterology Authors: Source Type: research
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