Wnt targets genes are not differentially expressed in desmoid tumors bearing different activating β-catenin mutations

ConclusionsNo differences in the expression levels of Wnt target genes were observed between the different CTNNB1 mutation types in DTF tumors. Further studies are needed to decipher the mechanism accounting for the diverse disease courses between DTF patients with different CTNNB1 variants.
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research