From Levinthal's Paradox to the Effects of Cell Environmental Perturbation on Protein Folding.

CONCLUSION: This paper concludes that the cellular environment could directly intervene in protein folding. The long-term interactions of the cellular environment and sequence evolution may enable proteins to fold efficiently. Therefore, to correctly understand the folding mechanism of proteins, the effect of the cellular environment on protein folding should be considered. PMID: 30332937 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30332937?dopt=Abstract

Source: Current Medicinal Chemistry - October 17, 2018 Category: Chemistry Authors: Zeng J, Huang Z Tags: Curr Med Chem Source Type: research

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