Pulmonary follicular lymphoma showing diffuse micronodules mimicking sarcoidosis.

Pulmonary follicular lymphoma showing diffuse micronodules mimicking sarcoidosis. Intern Med. 2018 Oct 17;: Authors: Takuma K, Eri H, Satoshi I, Takashi O PMID: 30333400 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research

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A 60-year-old multi-morbid male patient with polycystic kidney disease and secondary chronic renal insufficiency stage G5 A3 according to Kidney Disease: Improving Global Outcomes (KDIGO) classification was referred to our hospital with radiological differential diagnoses of sarcoidosis, ectasia of the pulmonary arteries, lymphoma, or central bronchial carcinoma with contralateral hilar lymph node metastases. He had concomitant arterial hypertension, manifest osteoporosis due to renal osteopathy, secondary compensated renal hyperparathyroidism, compensated metabolic renal acidosis, and diabetes mellitus type 2.
Source: Heart, Lung and Circulation - Category: Cardiology Authors: Tags: Image Source Type: research
We present here preliminary descriptive data on the patients' characteristics and their established diagnosis at follow-up.Methods: Since 2015, all patients aged ≥15 years and referred to the hematology or internal medicine department in 117 French hospitals, with an unexplained SM diagnosis (confirmed by echography or CT-scan with a craniocaudal length ≥13 cm) have been invited to participate. Unexplained cause of SM was defined as a first negative clinical workup based on patient's interview and physical examination, and biological routine tests (including complete blood and reticulocytes count, clotting test, live...
Source: Blood - Category: Hematology Authors: Tags: 903. Outcomes Research-Non-Malignant Hematology: Poster III Source Type: research
Conclusion: Routine microbiological testing on EBUS samples had a low yield for impactful clinical results in our cohort suggesting that such practise has limited utility.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional Pulmonology Source Type: research
In cases of hard rubbery lymph nodes like in Sarcoidosis and Lymphoma, it is sometimes difficult to obtain optimum cytology samples during EBUS TBNA (Transbronchial needle aspiration cytology) and thus the diagnostic yield of EBUS TBNA samples drops down to 60%. An EBUS TBNB sample from such lymph nodes can help to increase the diagnostic yield.Methods: We did a Pilot study in patients presenting with hard rubbery lymph nodes during EBUS TBNA, EBUS guided Transbronchial biopsy of the subcarinal lymph node was done with small size biopsy forceps. Diagnostic yield of biopsy samples was compared with EBUS TBNA cytology result...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional Pulmonology Source Type: research
Conclusion: Trasparietal biopsy under CT control consider diagnostically beneficial method, relatively safe.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional Pulmonology Source Type: research
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and positron emission tomography (PET) standard uptake values (SUV) are useful methods for evaluating mediastinal lymph node pathology.The aim this study was to compare EBUS TBNA and PET suv results in benign, granulomatous and malignant disease. The files of 151 patients who had FDG-PET scanning and underwent EBUS-TBNA between 2015-2017 were reviewed. The diagnoses were confirmed by needle aspiration cytology, histopathology and clinical follow-up. Malignant diseases included lung cancers, metastasis and lymphomas. Granulomatous diseases were mai...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung Cancer Source Type: research
Conclusion: 25G ProCore biopsy needles have a similar granuloma detection rate in patient with sarcoidosis type I and II compared to the conventional 22G needles.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional Pulmonology Source Type: research
Conclusion: Endosonography with nodal sampling is safe, feasible and has a high granuloma detecting rate and sensitivity for diagnosing stage I / II sarcoidosis, which is independent of the sampling route (endobronchial vs transesophageal).
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional Pulmonology Source Type: research
Conclusion: Awake EUS-B is a safe, well tolerated procedure that can be done without sedation in patients with high risk for sedation.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional Pulmonology Source Type: research
Granulomatous myopathy is a clinically and etiologically heterogeneous group of uncommon inflammatory myopathies, pathologically characterized by the presence of granulomas in skeletal muscle. Granulomas may contain necrosis as typically seen in infectious disorders (fungal, tuberculosis, or brucellosis) [1-3] or may occur without necrosis, so-called non-necrotizing or non-caseating granulomas. Various disorders were reported in association with non-caseating granulomatous myopathy, including sarcoidosis and less commonly other autoimmune diseases (Crohn's disease, anti-mitochondrial autoimmunity with or without primary bi...
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
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