Cardiovascular images: vascular hamartoma of the mitral valve in a horse

Publication date: December 2018Source: Journal of Veterinary Cardiology, Volume 20, Issue 6Author(s): M.J. DiVincenzo, J.D. Bonagura, L. Rings, T.A. Burns, R.E. Cianciolo, R. KohnkenAbstractAn 8-month-old Hanoverian gelding was presented with a history of cardiac murmurs that were not apparent as a foal nor reported at the time of castration. Major echocardiographic findings included mitral valvular thickening, functional stenosis, and mitral regurgitation of sufficient severity to cause diastolic and systolic cardiac murmurs, left-sided volume overload, and pulmonary hypertension. Due to the hemodynamic severity of the lesion and poor prognosis for future performance and longevity, euthanasia was elected. On gross postmortem examination, there was focal fibrous epicarditis affecting the heart base, and the left atrium was moderately dilated. The mitral valve surface was irregular and contained several nodules along the atrial face of the cusp. Histologically, this lesion was diagnosed as a vascular hamartoma, which is rarely reported in veterinary species and has not been described in heart valves. This benign proliferative lesion, and concurrent valvular dysfunction, was associated with an unusual manifestation of clinically evident disease and should be differentiated from common incidental valvular lesions such as hematocysts.
Source: Journal of Veterinary Cardiology - Category: Veterinary Research Source Type: research