Development of Novel Animal Model for Studying Scoliosis Using a Noninvasive Method and Its Validation through Gene-Expression Analysis.

Conclusions: Bracing is a noninvasive method for inducing scoliosis in an animal model with 100% reliability and with corresponding changes in gene expression. Scoliosis does not just involve a spine deformity, but can be referred to as a systemic disease on the basis of the pathological changes observed in various internal organs. PMID: 30326691 [PubMed - as supplied by publisher]
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research