Influence of membrane lipid composition on the structure and activity of γ-secretase

Phys. Chem. Chem. Phys., 2018, Accepted Manuscript DOI: 10.1039/C8CP04138E, PaperRodrigo Aguayo-Ortiz, John Straub, Laura Dominguez γ-Secretase (GS) is a multi-subunit membrane-embedded aspartyl prote-ase that cleaves more than 80 integral membrane proteins, including the amyloid precursor protein (APP) to produce the amyloid-β (Aβ) peptide. Oligomerization and... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Phys. Chem. Chem. Phys. latest articles - October 18, 2018 Category: Chemistry Authors: Rodrigo Aguayo-Ortiz Source Type: research