Emergence of Resistance to Fluconazole in Candida albicans Isolated From Vaginal Discharge

AbstractPurpose of ReviewTo provide information about the emergence of fluconazole resistance inCandida albicans isolated from vaginal discharge, in a global context, and to update the in vitro susceptibility profile of this species from Argentina.Recent FindingsVulvovaginal candidiasis is the second most common vaginal infection after vaginal bacteriosis.C. albicans remains the prevalent etiological yeast species, and despite antifungal treatment, the rate of recurrence remains high, which may be associated to antifungal resistance.SummaryData here presented were obtained from the study ofC. albicans strains isolated from patients with clinical signs of vulvovaginal candidiasis from 1996 to 2017. Data obtained could represent the susceptibility profile ofC. albicans strains circulating in Argentina and could be of potential usefulness to monitor and guide therapy, and also suggests the need for greater surveillance programs to detect fluconazole resistance over time.
Source: Current Fungal Infection Reports - Category: Infectious Diseases Source Type: research