Medical management of opioid-induced constipation differs from other forms of condition

(American Gastroenterological Association) Traditional laxatives are recommended as first-line agents to treat patients with a confirmed diagnosis of opioid-induced constipation, according to a new guideline from the American Gastroenterological Association. If an adequate trial of laxatives results in suboptimal symptom control, the guidelines recommend peripherally-acting mu-opioid receptor antagonist (PAMORA) drugs, namely naldemedine, naloxegol and methylnatrexone.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news