Thalamic and dentate nucleus abnormalities in the brain of children with Gaucher disease

We report three cases of GD with previously undescribed brain MRI changes mainly affecting the thalami and/or the dentate nuclei. We discuss the possible etiopathogenesis of these abnormalities. Correlation between brain MRI abnormalities, neurological symptoms, and treatment efficacy is still unclear.

Source: Neuroradiology - October 17, 2018 Category: Radiology Source Type: research