In vivo and in vitro assessment of the bleaching effectiveness of a brush-off patch containing 3.0% hydrogen peroxide

AbstractObjectivesTo evaluate the efficacy of a brush-off patch containing 3.0% hydrogen peroxide, which is a new over-the-counter (OTC) product for tooth whitening, and determine the optimal protocol for use.Materials and methodsWe performed an in vitro study using hydroxyapatite specimens and a clinical trial involving 140 volunteers. The brush-off patch was applied to the specimens (in vitro) or the maxillary anterior teeth (in vivo; 14  days) for 10 min twice daily (case 10 group) or 30 min once daily (case 30 group). We also included control groups in both experiments. Lightness (L*), redness (a*), and yellowness (b*) values were measured using a colorimeter. In the in vivo study, color changes were measured at baseline and 7 and 14  days after the start of patch application. The overall color change (ΔE) was statistically analyzed.ResultsIn the in vitro study, the color change ( ΔE*) after the experiment was significantly different between the two case groups and the control group (p 
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research

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