Measures of single- versus multiple-round translation argue against a mechanism to ensure coupling of transcription and translation [Microbiology]

In prokaryotes, the synthesis of RNA and protein occurs simultaneously in the cytoplasm. A number of studies indicate that translation can strongly impact transcription, a phenomenon often attributed to physical coupling between RNA polymerase (RNAP) and the lead ribosome on the nascent mRNA. Whether there generally exists a mechanism to...

Source: Proceedings of the National Academy of Sciences - October 16, 2018 Category: Science Authors: Menglin Chen, Kurt Fredrick Tags: Biological Sciences Source Type: research