The First Case of Hand Infection Caused by Dermabacter jinjuensis in a Symmetrical Peripheral Gangrene Patient
ConclusionThis is the first reported case of a human D. jinjuensis infection. We were able to treat patients without any complications by operative treatment and administering appropriate antimicrobial agents according to antibiotics susceptibility test.
ConclusionCondom catheter is frequently used to manage male urinary incontinence but it should not be used carelessly or overlooked as it can cause severe complications such as penile strangulation and penile gangrene.
Peripheral arterial disease (PAD) is a highly prevalent, yet underdiagnosed, condition . Although frequently asymptomatic, it is a leading cause of leg pain, claudication, ulceration, gangrene, and even amputation. On the other hand, patients with type 2 diabetes (T2DM) are more likely to develop PAD than do the non-diabetic subjects. Furthermore, they are affected by more severe and extensive form of the disease that tends to involve more distal arteries, progress more quickly, and also it is more likely to lead to ischemic ulceration and amputation .
ConclusionIn randomised, placebo-controlled trials of patients with T2DM, ipragliflozin was well tolerated, with a similar overall incidence of TEAEs to placebo. No new safety signals were observed.Trial Registration NumbersNCT01071850, NCT00621868, NCT01057628, NCT01117584, NCT01135433, NCT01225081, NCT01242215, NCT02175784, NCT01505426, NCT02452632, NCT02794792, NCT01316094.FundingAstellas Pharma Inc.
Authors: Shima N, Akiyama Y, Yamamoto S, Kokuzawa A, Nagatani K, Iwamoto M, Matsubara D, Kawai S, Sato K, Minota S Abstract A 48-year-old woman with severe pain and numbness of her right leg and foot was admitted to our hospital. She had never smoked and had little exposure to passive smoking. Initially, polyarteritis nodosa with anti-phospholipid antibodies was considered. Combination therapy with methylprednisolone pulse therapy, intravenous cyclophosphamide pulse therapy, vasodilators, antiplatelet agents, and anticoagulants was not effective. Vasculopathy was progressive, and she presented with gangrene of the ...
Jyotsna PunjIndian Journal of Anaesthesia 2019 63(10):851-855 Medical management along with stellate ganglion block is frequently given to prevent the vasculitis of fingers in patients of systemic lupus erythematosus (SLE). Bilateral stellate ganglion block is rarely given due to the concern of phrenic and recurrent laryngeal nerve palsy. In this article, we describe the management of a recently diagnosed SLE patient presented with progressive gangrene of fingers of both upper limbs. Meticulously planned serial bilateral ultrasound-guided stellate ganglion blocks were successfully given to prevent impending loss of digits...
Authors: Agarwal P, Gautam A, Bansal M, Jose R, Upadhyay S PMID: 31571461 [PubMed - in process]
This article provides non-radiologists with a systematic approach to identifying emergency pathology on abdominal and pelvic CT scans. It reviews the relevant cross-sectional anatomy and discusses the CT appearances of bowel perforation, bowel obstruction, bowel ischaemia (gangrene), bleeding, appendicitis and hydronephrosis using illustrative examples from the authors' clinical practice. Underlying causes for these conditions and the importance of interpreting the radiological appearances in conjunction with the patient's clinical condition and history are discussed. The authors hope that by using the POGBAH acronym and a...
This article explains how to diagnose and manage scrotal emergencies such as testicular torsion, Fournier gangrene, and testicular trauma. These diagnoses are often difficult to discern from less-concerning causes. This article helps to elucidate the differences between the dangerous and the less-harmful pathologic conditions. PMID: 31563197 [PubMed - in process]
We report a case of a female patient with rapidly advancing blue discoloration of her feet. Peripheral artery disease (PAD) and thrombosis were quickly ruled out. Eventually, she required transmetatarsal amputation for gangrene. Pathologic analysis confirmed the unexpected diagnosis of fibromuscular dysplasia (FMD), an arterial disease that most frequently causes renal and carotid artery stenosis. Common symptoms include secondary hypertension refractory to antihypertensives, dizziness and pulsatile tinnitus, and abdominal pain due to mesenteric artery involvement.