A whole methylome study of ethanol exposure in brain and blood: an exploration of the utility of peripheral blood as proxy tissue for brain in alcohol methylation studies.

CONCLUSIONS: Overall, we have shown some methylation changes in brain and blood after acute ethanol administration and that the changes in blood partly mirror the changes in brain suggesting the potential for DNA methylation in blood to be biomarkers of alcohol use. This article is protected by copyright. All rights reserved. PMID: 30320886 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30320886?dopt=Abstract

Source: Alcoholism, Clinical and Experimental Research - October 15, 2018 Category: Addiction Authors: Clark SL, Costin BN, Chan RF, Johnson AW, Xie L, Jurmain JL, Kumar G, Shabalin AA, Pandey AK, Aberg KA, Miles MF, van den Oord E Tags: Alcohol Clin Exp Res Source Type: research