Diallyl Trisulfide Protects Motor Neurons from the Neurotoxic Protein TDP-43 via Activating Lysosomal Degradation and the Antioxidant Response.

This study extends the findings of prior reports indicating that lower doses of DATS mediate cell survival in part by inducing autophagy and activating the Nrf2/antioxidant response element pathway.
PMID: 30317421 [PubMed - as supplied by publisher]

Source: Neurochemical Research - October 13, 2018 Category: Neuroscience Authors: Liu C, Leng B, Li Y, Jiang H, Duan W, Guo Y, Li C, Hong K Tags: Neurochem Res Source Type: research