Contribution of white matter lesions to cognitive decline in Parkinson's disease

In this prospective longitudinal study, the relationship between white matter lesions (WML), manually delineated on MRI, and cognitive decline over a two-year period was examined in 34 patients with Parkinson's disease (PD). WML was associated with clinically important cognitive impairment in PD, i.e. the transition from normal cognition to mild cognitive impairment (MCI). (see Fig. 1)

Source: Parkinsonism and Related Disorders - October 15, 2018 Category: Neurology Authors: Michael Teodor Grey, Branislav Vesel ý, Martin Gajdoš, Patrícia Klobušiaková, Ivan Rektor Tags: Correspondence Source Type: research