Presentation, etiology, and outcome of brain infections in an Indonesian hospital: A cohort study

Conclusion In this setting, patients with CNS infections present late with severe disease and often associated with advanced HIV infection. Tuberculosis, toxoplasmosis, and cryptococcosis are common. High mortality and long-term morbidity underline the need for service improvements and further study.
Source: Neurology Clinical Practice - Category: Neurology Authors: Tags: Encephalitis, Meningitis, HIV, Prognosis Research Source Type: research

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Publication date: Available online 15 January 2020Source: Ticks and Tick-borne DiseasesAuthor(s): Dana Zubriková, Maria Wittmann, Václav Hönig, Pavel Švec, Bronislava Víchová, Sandra Essbauer, Gerhard Dobler, Libor Grubhoffer, Kurt PfisterAbstractLyme borreliosis and tick-borne encephalitis (TBE) are the most common tick-borne diseases in Germany. We collected Ixodes ricinus ticks from 16 high-risk and four low-risk sites distributed in Lower Bavaria and Upper Palatinate based on the number of human TBE cases recorded at the Robert Koch Institute from 2001 to 2009. A total of 8805 qu...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Link N suppresses interleukin-1β-induced biological effects on human osteoarthritic cartilage. Eur Cell Mater. 2020 Jan 15;39:65-76 Authors: Alaqeel M, Grant MP, Epure LM, Salem O, AlShaer A, Huk OL, Bergeron SG, Zukor DJ, Kc R, Im HJ, Anbazhagan AN, Antoniou J, Mwale F Abstract Osteoarthritis (OA) is a disease of diarthrodial joints associated with extracellular matrix proteolytic degradation under inflammatory conditions, pain and disability. Currently, there is no therapy to prevent, reverse or modulate the disease course. The present study aimed at evaluating the regenerative potential of Link...
Source: European Cells and Materials - Category: Cytology Tags: Eur Cell Mater Source Type: research
This appeared a day or so ago.Increasing fire threat to vulnerable telecommunications networksBy Fergus Hunter and Zoe SamiosJanuary 11, 2020 — 12.00amAustralia's unprecedented bushfire crisis has exposed the vulnerability of phone and internet networks, prompting Communications Minister Paul Fletcher to warn telecommunications giants to prepare for increasingly severe disasters.As dozens of mobile towers went dark during this summer's catastrophic bushfires, people have been cut off from contact with emergency services and in some cases unable to pay for essential supplies. Telcos have scrambled to bolster their net...
Source: Australian Health Information Technology - Category: Information Technology Authors: Source Type: blogs
The lives of persons living with mental illness are affected by psychological, biological, social, economic, and environmental factors over the life course. It is therefore unlikely that simple preventive strategies, clinical treatments, therapeutic interventions, or policy options will succeed as singular solutions for the challenges of mental illness. Persons living with mental illness receive services and supports in multiple settings across the health care continuum that are often fragmented, uncoordinated, and inadequately responsive. Appropriate assessment is an important tool that health systems must deploy to respo...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
ae-Ho Hwang Oncolytic viruses are a promising class of anti-tumor agents; however, concerns regarding uncontrolled viral replication have led to the development of a replication-controllable oncolytic vaccinia virus (OVV). The engineering involves replacing the native thymidine kinase (VV-tk) gene, in a Wyeth strain vaccinia backbone, with the herpes simplex virus thymidine kinase (HSV-tk) gene, which allows for viral replication control via ganciclovir (GCV, an antiviral/cytotoxic pro-drug). Adding the wild-type HSV-tk gene might disrupt the tumor selectivity of VV-tk deleted OVVs; therefore, only engineered viruses t...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
ConclusionsOur patient ’s case highlights the importance of assessing the clonal relationships of the lymphoid components of a composite lymphoma and Epstein-Barr virus screening in mucosa-associated lymphoid tissue lymphoma in patients with autoimmune disease.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Publication date: March 2020Source: Human Pathology: Case Reports, Volume 19Author(s): Sofiene Bouali, Kamel Bahri, Alia Zehani, Khalil Ghedira, Khansa Abderrahmen, Jalel KallelAbstractIntracranial tuberculoma mostly occurs in supratentorial location in adult patients and there are isolated cases with Infratentorial tuberculoma reported in the literature in the last 10 years. A 49-year-old man presented with progressive staggering gait and headache for 3 months and was diagnosed with a giant cerebullar tuberculoma. Although rare, our case demonstrates that tuberculoma should be considered in the differential diagnosis ...
Source: Human Pathology: Case Reports - Category: Pathology Source Type: research
This study was conducted between January 1, 2019, and July 25, 2019, at the neurology and biochemistry clinics of two different tertiary hospitals simultaneously. Overall, 50 RRMS patients with migraine, 50 RRMS patients without migraine, and 50 healthy volunteers were included in the study. The participants’ vitamin D, VITDBP, VITDR, hs-CRP, SOD, CAT, GSH-Px, TAS, TOS, and OSI values were measured.Results: The vitamin D and VITDR values of the RRMS patients with migraine were lower than those of the RRMS patients without migraine (respectively, p = 0.014, p
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
This summer's record-breaking outbreak of Eastern equine encephalitis highlights the importance of cities and states ability to prepare for and respond to vectorborne disease threats.
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: Eastern Equine Encephalitis (EEE) MMWR Morbidity & Mortality Weekly Report Mosquito-Borne Diseases Source Type: news
AUGUSTA, Maine (AP) — Maine reported a record number of Lyme disease cases last year, and the number could rise as data continues to trickle in, officials said Thursday. There were at least 2,079 cases in 2019, the Maine Center for Disease Control and Prevention reported. It’s too early to say why the numbers grew last year. But the numbers underscore the importance of taking precautions to avoid tick bites, said Dr. Nirav Shah, director of the Maine CDC. Winter is a time of low ticket activity. But ticks can be active when the temperature climbs above 40, as it did last weekend in Maine. The state also experie...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated CBSN Boston LYME DISEASE Maine news ticks Source Type: news
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