Intermittent inhaled tobramycin and systemic cytokines response in CF patients with Pseudomonas aeruginosa.

CONCLUSIONS: The results of lung function parameters support the relative stability of CF patients during the month off therapy; however, the difference in serum IL-6 raises the possibility of ongoing higher degrees of inflammation during the month off therapy with TIP. The small sample size and the multiple parameters evaluated preclude firm conclusions; therefore, larger multicenter studies are needed to assess the on/off treatment strategy.
PMID: 30315749 [PubMed - in process]

Source: Clinical and Investigative Medicine - September 30, 2018 Category: Biomedical Science Authors: Toukan Y, Gur M, Hakim FH, Geffen Y, Bar-Yoseph R, Nir V, Bentur L Tags: Clin Invest Med Source Type: research