Regiocontrol in the cobalt-catalyzed hydrosilylation of alkynes.

Regiocontrol in the cobalt-catalyzed hydrosilylation of alkynes.
Chem Commun (Camb). 2018 Oct 12;:
Authors: Wu G, Chakraborty U, Jacobi von Wangelin A
Abstract
Hydrofunctionalizations of unsaturated hydrocarbons are key strategies for the synthesis of functionalized building blocks. Here, we report highly versatile cobalt-catalyzed hydrosilylations of alkynes that operate with minute amounts of the inexpensive, bench-stable pre-catalyst Co(OAc)2·4H2O under mild conditions (0.1-1 mol%, THF, r.t., 1 h). Near-perfect regiocontrol/stereocontrol was induced by the choice of the ligand: bidentate phosphines afforded (E)-β-vinylsilanes; α-vinylsilanes formed with bipyridine ligands.
PMID: 30310911 [PubMed - as supplied by publisher]

Source: Chemical Communications - October 12, 2018 Category: Chemistry Authors: Wu G, Chakraborty U, Jacobi von Wangelin A Tags: Chem Commun (Camb) Source Type: research