Dietary Weight Loss in Insulin-resistant Non-obese Humans: Metabolic Benefits and Relationship to Adipose Cell Size

ConclusionsWeight loss yields metabolic health benefits in insulin-resistant overweight adults, even in the absence of classic cardiovascular risk factors. Weight loss-related improvement in insulin sensitivity may be mediated through changes in adipose cell size and/or central distribution of body fat. The insulin-resistant subgroup of overweight individuals should be identified and targeted for dietary weight loss.Clinical Trials IdentifierNCT00186459.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research