Simultaneous determinations of four major bioactive components in Acacia catechu (L.f.) Willd and Scutellaria baicalensis Georgi extracts by LC–MS/MS: Application to its herb–herb interactions based on pharmacokinetic, tissue distribution and excretion studies in rats

ConclusionThis is the first report to evaluate the pharmacokinetics, tissue distribution and excretion of co-administration of ACW or SBG to rats and compared its properties of four major bioactive components. The results demonstrate that herb –herb interactions occurred in this herb couple.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research