Telomerase activation and ATRX mutations are independent risk factors for metastatic pheochromocytoma and paraganglioma.

CONCLUSION: Assessment of telomerase activation and ATRX mutations could be used to identify metastatic PPGL, particularly in tumors at high-risk of progression. PMID: 30301828 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30301828?dopt=Abstract

Source: Clinical Cancer Research - October 9, 2018 Category: Cancer & Oncology Authors: Job S, Draskovic I, Burnichon N, Buffet A, Cros J, Lépine C, Venisse A, Robidel E, Verkarre V, Meatchi T, Sibony M, Amar L, Bertherat J, de Reyniès A, Londoño-Vallejo A, Favier J, Castro-Vega LJ, Gimenez-Roqueplo AP Tags: Clin Cancer Res Source Type: research