Effect of light-emitting diodes, platelet-rich plasma, and their combination on the activity of sheep tenocytes

This study utilizes cell culture to explore the potential effect of light-emitting diode and/or growth factors in the form of platelet-rich plasma (PRP) on the activity of tenocytes isolated from sheep Achilles tendons by measuring the cell metabolism and cell mobility using cell viability and migration assays to proof safety and confirm activity. Results showed that sheep tenocyte-cultured groups treated with 5% platelet-rich plasma alone or combined with 4  J/cm2 light-emitting diode have increased viability significantly when compared to control group after a 48  h, while light-emitting diode treatment has not decreased cell migration significantly when compared with control. Result suggests that using platelet-rich plasma alone or combined with light-emitting diode might have potential to enhance healing response at the conditions applied. PRP could enhan ce proliferation while LED could enhance migration and proliferation. Further research is needed at longer durations.
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research