Experimental research into the potential therapeutic effect of GYY4137 on Ovariectomy-induced osteoporosis.

Conclusions: Through the slow release of H2S, GYY4137 did an excellent job of simulating endogenous neuroendocrine gaseous signaling molecules. Exogenous H2S had a regulatory effect on osteoporosis in ovariectomized rats, showing potential value for the treatment of human postmenopausal osteoporosis.
PMID: 30305826 [PubMed - in process]

Source: Cellular and Molecular Biology Letters - October 13, 2018 Category: Biochemistry Authors: Xu ZS, Dai F, Chen J, Lv M, Cheng JW, Zhang XM, Lin BW Tags: Cell Mol Biol Lett Source Type: research