Sam domains in multiple diseases.

CONCLUSION: Considering the many roles of the Sam domain into a significant variety of diseases, more efforts and novel drug discovery campaigns need to be engaged to find out small molecules and/or peptides targeting Sam domains. Such compounds may represent the pillars on which to build novel therapeutic strategies to cure different pathologies.
PMID: 30306850 [PubMed - as supplied by publisher]

Source: Current Medicinal Chemistry - October 9, 2018 Category: Chemistry Authors: Vincenzi M, Mercurio FA, Leone M Tags: Curr Med Chem Source Type: research