Investigational Infertility Tx; Vit D Disappoints for Fracture Prevention; World Obesity Day

(MedPage Today) -- News and commentary from the endocrinology world
Source: MedPage Today Cardiovascular - Category: Cardiology Source Type: news

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Conclusion(s)The presence of lipid receptors/transporters and HSL in human spermatozoa suggests their role in the process of maturation/capacitation. The changes in the expression of lipid receptors/transporters and the lack of the 130-kDa HSL isoform in obese patients prevent the hydrolysis of cholesterol esters internalized by these receptors, and favor their accumulation in the cytoplasm of the spermatozoa that could contribute to lipotoxicity and infertility.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
Polycystic ovarian syndrome (PCOS) is of frequent occurrence in Saudi females and is often associated with obesity, insulin resistance, hypogonadotropic hypogonadism, and infertility. Since these features are ...
Source: BMC Women's Health - Category: OBGYN Authors: Tags: Research article Source Type: research
Obesity has an inverse association with female reproductive potential that includes increased time to conception [1], increased lifetime odds of nulliparity [2,3], and decreased efficacy of treatment options for infertility [4]. For patients with severe obesity (body mass index, BMI ≥ 40 kg/m2 or 35 to
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
The preconceptional period may be an optimal window of opportunity to improve lifestyle. We previously showed that a 6  month preconception lifestyle intervention among women with obesity and infertility was su...
Source: International Journal of Behavioral Nutrition and Physical Activity - Category: Nutrition Authors: Tags: Research Source Type: research
Bradley Goldman has filled out a size large T-shirt his whole adult life. As a bodybuilder, he knew that a steady stream of lean, bland proteins, heavy weights and steroids would make his muscles pop. But over the past six months, Goldman, a fitness and nutrition consultant in Los Angeles, has watched his jacked physique soften and shrink. “I cracked a couple of weeks ago, and I had to buy a shirt a whole size smaller,” he says. He tried it on for his wife Brittany, and it hung loose on his frame. “I just kind of shook my head,” he says. He knew she saw the changes too. Goldman, now 30, began takin...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized fertility Research Source Type: news
AbstractIntroductionLarge observational studies have shown that obstetric and perinatal outcomes are negatively affected in obese women. In contrast, a recent Dutch randomized trial of infertile women and lifestyle weight intervention found no difference between the weight intervention group and the control group in obstetric or neonatal outcomes. We have recently published a large Nordic randomized trial where obese women scheduled for in vitro fertilization (IVF) treatment went through an intensive weight intervention treatment prior to IVF. No significant effect on live birth rate was found, despite large weight loss in...
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: Original Research Article Source Type: research
Authors: Tsang SH, Aycinena ARP, Sharma T Abstract Bardet-Biedl syndrome (BBS) is an autosomal recessive disease with a prevalence of about 1/125,000. The syndrome involves mixed rod-cone dystrophy (which becomes obvious by 6 years of age). About two thirds of patients have postaxial polydactyly, and sometimes syndactyly, brachydactyly, and/or clinodactyly may be present. Hypogonadism and renal involvement occur in about 40%, mental retardation in about 50%, and truncal obesity in about 70%; it is present early, along with insulin resistance, type 2 diabetes, dyslipidemia, and hypertension. Vision becomes ma...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Source: Gynecological Endocrinology - Category: Endocrinology Authors: Source Type: research
CONCLUSIONS: Stress and obesity may induce male infertility by disrupting both sperm quality and testis histology. When stress and obesity are coexisting, these adverse effects are more severe. And also, increased GAT1 expression may be associated with these effects. PMID: 30566207 [PubMed - as supplied by publisher]
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
Condition:   Infertility Interventions:   Diagnostic Test: Visceral fat thickness;   Diagnostic Test: Body mass index Sponsor:   Assiut University Not yet recruiting
Source: - Category: Research Source Type: clinical trials
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