Guiding diabetes screening and prevention: rationale, recommendations and remaining challenges.

Guiding diabetes screening and prevention: rationale, recommendations and remaining challenges. Expert Rev Endocrinol Metab. 2015 Jul;10(4):381-398 Authors: Aroda VR, Getaneh A Abstract Advances made in diabetes management are not sufficient to reduce morbidity, mortality and cost without making prevention efforts at various levels imperative for substantial impact. Research has demonstrated the efficacy of lifestyle intervention and medications in preventing type 2 diabetes among diverse high-risk groups commonly identified with oral glucose tolerance testing. Efficacy, sustainability and safety data are most comprehensive for lifestyle and metformin, with other medications also demonstrating efficacy and potential in the pharmacoprevention of diabetes. Subsequent implementation studies have demonstrated feasibility of lifestyle intervention programs at health centers, communities, and at local and national government levels. Challenges remain in widespread translation and reaching and engaging at-risk individuals and populations. PMID: 30293496 [PubMed]
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research

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ConclusionFindings highlight the importance of rethinking the way in which South Asians are labelled as a homogenous group and accounting for such differences when adapting and designing culturally-tailored DSME and or DSMS interventions in clinical practice.
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Publication date: August 2019Source: Biomedicine &Pharmacotherapy, Volume 116Author(s): Anand P. Gupta, Pragati Singh, Richa Garg, Guru R. Valicherla, Mohammed Riyazuddin, Anees A. Syed, Zakir Hossain, Jiaur R. GayenAbstractAimsTo investigate the role of pancreastatin inhibitor (PSTi8) in lipid homeostasis and insulin sensitivity in dexamethasone induced fatty liver disease associated type 2 diabetes.Main methodsGlucose releases assay, lipid O staining and ATP/AMP ratio were performed in HepG2 cells. Twenty four mice were randomly divided into 4 groups: Control group (saline), DEX (1 mg/kg, im) for 17 days, DEX+...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
This study is a retrospective study based on medical records. Differences in the reactive hyperemia index (RHI) among the groups and factors affecting the RHI in each group was analyzed. The vascular endothelial function was assessed by measuring the RHI using peripheral arterial tonometry. Patients The study subjects were 114 patients with non-functional thyroid tumors (healthy n=14), T2DM (T2DM n=64), and RA (RA n=36). Results The RHI was 2.29 in the control, 1.85 in the T2DM, and 1.83 in the RA group, with values lower in the T2DM and RA groups than in the control group (p=0.033) but not markedly different between the t...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
DIABETES type 2 risk could be lowered by making some diet or lifestyle changes. You could avoid high blood sugar symptoms and signs by eating this breakfast cereal every day.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Conclusions:Women with GD history demonstrated high risk of developingT2D. Simple changes of lifestyle were shown to be an effcient prevention protocol. Despite therapeutical education, few women spontaneously complied with T2D screening. The telephone reminders could improve the screening observance therefore patient ’s outcome.Keywords:Diabetes mellitus, follow ‑up, gestational diabetes
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Background:The aim is to investigate the association between diet quality and daily price of foods consumed among Iranian diabetic patients.Methods:This cross ‑sectional study was conducted among 200 patients with type 2 diabetes mellitus (T2DM) aged 30–70 years. General information, socioeconomic status, anthropometric and biochemical characteristics, and food prices were collected by pretested questionnaires. Dietary intakes were assessed using a se mi‑quantitative reliable and valid food frequency questionnaire. Modifed nutritionist IV and SPSS software were used for analyses.Results:The results of the present...
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
CONCLUSIONS: Serum ALP level was positively and independently associated with baPWV in men and women, suggesting that an elevated ALP level may be a useful surrogate marker for arterial stiffness in adult men and women. PMID: 31092766 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
AbstractAims/IntroductionTo investigate the efficacy/safety of dulaglutide once ‐weekly monotherapy versus glimepiride in Chinese patients with type 2 diabetes.Materials and MethodsThis was a post hoc analysis of a Chinese randomized, double ‐blind, noninferiority, phase 3 study. Patients (N=572) with inadequate glycemic control received dulaglutide 1.5 (n=189) or 0.75 (n=194) mg once‐weekly or glimepiride (1 to 3 mg/day; n=189) for 26 weeks. Primary objective: noninferiority of dulaglutide 1.5 mg versus glimepiride for the change f rom baseline to Week 26 in glycated hemoglobin (HbA1c; noninferiority margin: 0.4%).R...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Original Article Source Type: research
Authors: Agca R, Hopman LHGA, Laan KCJ, van Halm VP, Peters MJL, Smulders YM, Dekker JM, Nijpels G, Stehouwer CDA, Voskuyl AE, Boers M, Lems WF, Nurmohamed MT Abstract OBJECTIVE: Cardiovascular (CV) disease risk is increased in rheumatoid arthritis (RA). However, longterm follow-up studies investigating this risk are scarce. METHODS: CARRÉ is a prospective cohort study investigating CV disease and its risk factors in 353 patients with longstanding RA. CV endpoints were assessed at baseline, 3, 10 and 15 years after the start of the study and are compared to a reference cohort(n=2540) including a large nu...
Source: Journal of Rheumatology - Category: Rheumatology Tags: J Rheumatol Source Type: research
Authors: Quezada-Fernández P, Trujillo-Quiros J, Pascoe-González S, Trujillo-Rangel WA, Cardona-Müller D, Ramos-Becerra CG, Barocio-Pantoja M, Rodríguez-de la Cerda M, Nérida Sánchez-Rodríguez E, Cardona-Muñóz EG, García-Benavides L, Grover-Páez F Abstract Type 2 diabetes mellitus (T2DM) is associated with premature atherosclerosis and arterial stiffening due to the accumulation of advanced glycation end-products in vessel walls. Green tea polyphenols are considered cardio-protective substances. In this randomised double-blind placebo-contro...
Source: International Journal of Food Sciences and Nutrition - Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
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