Osteoporosis in pituitary diseases: lessons for the clinic.

Osteoporosis in pituitary diseases: lessons for the clinic. Expert Rev Endocrinol Metab. 2015 Mar;10(2):169-176 Authors: Bolanowski M, Jawiarczyk-Przybyłowska A, Halupczok-Żyła J Abstract Osteoporosis is a systemic disease characterized by bone mass and density loss leading to fragility fractures. Osteoporosis due to endocrine disorders is an example of secondary osteoporosis. The harmful effects on bones are common in patients harboring pituitary tumors (acromegaly, prolactinoma, Cushing's disease) and suffering from hypopituitarism. Increased fracture risk and high healthcare costs of fractured patients are their consequences. The coexistence of some of these disorders and hypogonadism results in severe osteoporosis. The influence of the certain diseases, their activity and therapy and accompanying hypogonadism on bone turnover, bone mineral density and fracture incidence is presented. PMID: 30293506 [PubMed]
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research