Quantifying the setup uncertainty of a stereotactic murine Micro-Image guided radiation therapy system.
CONCLUSIONS:: Cranial irradiation that can permit positional uncertainties on the order of a millimeter can rely solely on stereotactic coordinates derived from a single daily CBCT. Irradiations of subregions requiring sub-millimeter accuracy require daily image guidance for each mouse.
ADVANCES IN KNOWLEDGE:: This is the first investigation of stereotactic reproducibility using the X-RAD SmART and it suggests a method for increased efficiency in high throughput experiments.
PMID: 30299986 [PubMed - as supplied by publisher]
Source: The British Journal of Radiology - Category: Radiology Authors: Walb MC, Carlson BL, Sarkaria JN, Tryggestad EJ Tags: Br J Radiol Source Type: research