Comorbidities in patients with non-functioning pituitary adenoma: influence of long-term growth hormone replacement

Conclusion: The incidence of cerebral infarction is increased in patients with NFPA irrespective of GHRT. Patients without GHRT had an increased risk of T2DM, whereas patients with GHRT had a normal incidence of T2DM, despite having higher BMI. Incidence of malignant tumors was not increased. Thus, long-term GHRT seems to be safe regarding risk of comorbidities. PMID: 30299891 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30299891?dopt=Abstract

Source: European Journal of Endocrinology - October 1, 2018 Category: Endocrinology Authors: Hammarstrand C, Ragnarsson O, Bengtsson O, Bryngelsson IL, Johannsson G, Olsson DS Tags: Eur J Endocrinol Source Type: research