The Mechanical Ventilation-Respiratory Distress Observation Scale as a surrogate of self-reported dyspnoea in intubated patients

Intensive care unit (ICU) patients are exposed to many sources of discomfort, among which dyspnoea is one of the more severely distressing [1]. In invasively mechanically ventilated patients, dyspnoea is frequent (47% of intubated patients report breathing discomfort when they can first communicate with caregivers) and severe (median rating of 5 on a dyspnoea visual analogue scale (D-VAS); association with anxiety and neurovegetative signs of stress) [2]. It is often linked to ventilator settings and seems to be associated with poorer clinical outcomes (e.g. delayed extubation and post-traumatic stress disorders) [2, 3]. As in other settings, identifying and quantifying dyspnoea in mechanically ventilated patients is therefore a major clinical issue. This is challenging because self-report and self-assessment, prerequisites for D-VAS assessment [4], are often impossible or very difficult in this setting. Unfortunately, caregivers markedly underestimate dyspnoea in this context [5, 6]. The risk of occult respiratory suffering is therefore major in the ICU setting and neglecting it would amount to medical error [7].
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Research letters Source Type: research

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Altered Brain Function in Drug-Naïve Major Depressive Disorder Patients With Early-Life Maltreatment: A Resting-State fMRI StudyZhexue Xu1,2†, Jing Zhang1†, Di Wang3†, Ting Wang4, Shu Zhang5, Xi Ren2, Xiaolei Zhu7, Atsushi Kamiya7, Jiliang Fang6* and Miao Qu1,2*1Department of Neurology, Xuan Wu Hospital Capital Medical University, Beijing, China2Department of Neurology, Third Affiliated Hospital, Beijing University of Chinese Medicine, Beijing, China3Department of Clinical Psychology, Beijing Anding Hospital, Beijing, China4Nanjing Municipal Hospital of Traditional Chinese Medicine, Nanjing, China...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
ConclusionsSocial interactions are the most complex and ambiguous environments human beings place themselves in. Many explicit and implicit “rules” govern what is considered appropriate and what can be expected from any one interaction. Consequently, they are settings rife for miscommunication and misunderstanding. It requires intricate examination to determine exactly what the rewarding components of social interactions are. Social interactions are highly dynamic, complex circumstances that seem more inclined to produce anxiety than lead to rewards given their ambiguities. For those with social anhedonia, whos...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
DiscussionAs detailed above, the “elements” in both a classical and a contemporary sense have effects on our mental health and are potentially modifiable aspects that can be harnessed as therapeutic interventions. The most robust interventional evidence currently available shows tentative support for several use of the elements via horticultural and nature-exposure therapy, green exercise/physical activity, sauna and heat therapy, balneotherapy, and breathing exercises. It should be noted that, in many cases, these interventions were not studied in definitive diagnosed psychiatric disorders and thus it is prema...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusions: Most studies were of poor quality and results should be interpreted with caution. Overall moderate effects were found which decreased substantially when interventions were compared to active control. It is unclear whether meditation, yoga or mindfulness affect academic achievement or affect have any negative side effects. Introduction Rationale Every 12 months, between 7 and 16% of students in tertiary education experience a mood or anxiety disorder and a further 30% of students report experiencing moderate to severe levels of stress (1–4). It is important to tackle poor mental health early as ...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Zoe M. Tapp, Jonathan P. Godbout and Olga N. Kokiko-Cochran* Department of Neuroscience, Institute for Behavioral Medicine Research, College of Medicine, The Ohio State University, Columbus, OH, United States Each year approximately 1.7 million people sustain a traumatic brain injury (TBI) in the US alone. Associated with these head injuries is a high prevalence of neuropsychiatric symptoms including irritability, depression, and anxiety. Neuroinflammation, due in part to microglia, can worsen or even cause neuropsychiatric disorders after TBI. For example, mounting evidence demonstrates that microglia become &ld...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
In a recent study published in the journal of Depression and Anxiety, a voice-analyzing AI was able to detect, with 89% accuracy, if a subject presented with PTSD.  
Source: mobihealthnews - Category: Information Technology Source Type: news
TUESDAY, April 23, 2019 -- A speech-based algorithm can differentiate individuals with posttraumatic stress disorder (PTSD) from controls, according to a study published online April 22 in Depression and Anxiety. Charles R. Marmar, M.D., from the...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
Using computerized voice analysis, a new study found 18 features of speech that identify markers of PTSD in veterans.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Post-Traumatic Stress Disorder Veterans Psychology and Psychologists Mental Health and Disorders United States Defense and Military Forces Voice Recognition Systems Defense Department SRI International Depression and Anxiety (Journal) Source Type: news
CONCLUSIONS: The results from this first-of-kind pilot study suggest that including BJJ as a complementary treatment to standard therapy for PTSD may be of value. It will be necessary to validate these promising results with a larger subject cohort and a more rigorous experimental design before routinely recommending this complementary therapy. PMID: 31004163 [PubMed - as supplied by publisher]
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
We examined whether time to onset of paresthesia was associated with indicators of severity of World Trade Center (WTC) exposure. We analyzed data from 3411 patients from the Bellevue Hospital—WTC Environmental Health Center. Paresthesia was defined as present if the symptom occurred in the lower extremities with frequency “often” or “almost continuous.” We plotted hazard functions and used the log-rank test to compare time to onset of paresthesia between different exposure groups. We also used Cox regression analysis to examine risk factors for time-to-paresthesia after 9/...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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