Pneumonia-causing bacteria can be spread by nose picking and rubbing

This study is the first to show that transmission can occur via contact between the nose and the hands after exposure to pneumococcus bacteria.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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Conclusions: Although comorbidities derived through administrative data did produce an AUC greater than chart review, our analyses suggest a coding bias in several comorbidities with a paradoxically protective effect. Therefore, chart review, while labor and resource intensive, may be the ideal method for ascertainment of clinically relevant comorbidities.
Source: Medical Care - Category: Health Management Tags: Brief Report Source Type: research
Publication date: Available online 15 October 2018Source: Journal of Hospital InfectionAuthor(s): C.C.H. Leung, G.M. Joynt, C.D. Gomersall, W.T. Wong, A. Lee, L. Ling, P.K.S. Chan, P.C.W. Lui, P.C.Y. Tsoi, C.M. Ling, M. HuiSummaryWhereas high-flow nasal cannula use is gaining prevalence, its high gas flow raises concerns about aerosolization of infectious particles and spread of infection. This randomized controlled crossover non-inferiority trial (N = 20) evaluated the degree of environmental contamination by viable bacteria associated with the use of high-flow nasal cannula compared with conventional oxygen mask for crit...
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
Condition:   Ventilator-acquired Pneumonia Interventions:   Device: EVAC-PU-ETT;   Device: PVC-ETT Sponsors:   Oregon Health and Science University;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting
Source: - Category: Research Source Type: clinical trials
[Wellbeing Foundation] Lagos -Today, on Global Handwashing Day, the focus of the global health community is on the importance of handwashing with soap as a highly effective way to prevent the spread of disease and save lives. The evidence for handwashing is well-known -- it can dramatically reduce the risk of diarrhoea and pneumonia, and thwarts the spread of diseases like Ebola. Access to clean water, good sanitation and hygiene is also a significant factor in the prevention of blindness caused trachoma.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
The Journal of Dermatology, EarlyView.
Source: The Journal of Dermatology - Category: Dermatology Authors: Source Type: research
In this study, we evaluate the long-term efficacy and safety of everolimus for tuberous sclerosis complex (TSC)-associated treatment-refractory seizures. Methods After completion of the core phase, patients could enter an open-label extension phase and receive everolimus (target exposure, 3–15 ng/mL) for ≥48 weeks. Efficacy end points included change from baseline in average weekly SF expressed as response rate (RR, ≥50% reduction) and median percentage reduction (PR). Results Of 366 patients, 361 received everolimus in core/extension phases. The RR was 31% (95% CI, 26.2–36.1; N = 352) at week 18, 46.6%...
Source: Neurology Clinical Practice - Category: Neurology Authors: Tags: Class IV, All Epilepsy/Seizures Research Source Type: research
This article provides a balanced and comprehensive systematic critique of the literature in order to provide an up-to-date summary of its clinical pharmacology. Oral delafloxacin is rapidly absorbed and exhibits comparable exposure characteristics (300  mg intravenous versus 450 mg oral) between the two formulations, allowing easy transition from intravenous to oral therapy. The bioavailability is high (60–70%) and absorption is not affected by food intake, although further studies are required under clinically relevant conditions. Delafloxaci n is primarily excreted renally (thus requiring renal dose adjus...
Source: European Journal of Drug Metabolism and Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research
ConclusionsImipenem/relebactam could provide an important treatment option against infections with P. aeruginosa isolates that are non-susceptible to several currently available antipseudomonal β-lactams.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
(Natural News) One of the scariest health problems that the world is facing today is the explosion of antibiotic-resistant superbugs like methicillin-resistant staphylococcus aureus, or MRSA. These bacteria can cause infections, pneumonia, and other problems. When left unchecked – which is often the case because it’s notoriously difficult to treat – it can lead to...
Source: - Category: Consumer Health News Source Type: news
ConclusionEarly TTNT and EEG reactivity help to predict good neurological outcome in children undergoing therapeutic hypothermia after cardiac arrest. Seizures and status epilepticus may predict poor neurological outcome.
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
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