The Importance of A, B, Cs! Airways and Breathing Matter for Survival after Hematopoietic Stem Cell Transplantation

Pulmonary compromise has been shown to significantly contribute to nonrelapse mortality after hematopoietic stem cell transplantation (HSCT) [1-4]. The etiology of these pulmonary complications includes intrapulmonary causes of fibrosis and toxicities from treatment regimens or infections (ie, restrictive lung disease), graft-versus-host disease (GVHD) or bronchiolitis obliterans syndrome (BOS) (ie, obstructive lung disease), and vascular abnormalities (eg, pulmonary hypertension), as well as extrapulmonary causes, such as weakness or sclerodermatous GVHD.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research