Comparison of prefrontal hemodynamic responses and cognitive deficits between adult patients with autism spectrum disorder and schizophrenia

Autism spectrum disorder (ASD) and schizophrenia share many phenotypic characteristics, but their association with prefrontal function have not been directly compared. The aim of this study is to compare cognitive profiles and their association with the prefrontal function between the two groups. We explored prefrontal dysfunction among adult individuals with ASD (n  = 32), schizophrenia (n = 87), and healthy controls (HCs; n = 50). We assessed cognitive function in all participants using the Brief Assessment of Cognition in Schizophrenia (BACS).

Source: Schizophrenia Research - October 10, 2018 Category: Psychiatry Authors: Shenghong Pu, Kazuyuki Nakagome, Takahiro Satake, Hiroaki Ohtachi, Masashi Itakura, Takehiko Yamanashi, Akihiko Miura, Katsutoshi Yokoyama, Hiroshi Matsumura, Masaaki Iwata, Izumi Nagata, Koichi Kaneko Source Type: research