Stereoselective Synthesis of E-3-(Arylmethylidene)-5-(Alkyl/Aryl)-2(3H)-Furanones by Sequential Hydroacyloxylation-Mizoroki-Heck Reactions of Iodoalkynes

Org. Biomol. Chem., 2018, Accepted Manuscript DOI: 10.1039/C8OB02063A, PaperGopinathan Muthusamy, Sunil Vasant Pansare A modular, stereoselective synthesis of E-3-(arylidene)-5-(alkyl/aryl)-2(3H)-furanones was developed. The methodology features regioselective addition of β-aryl acrylic acids to iodoacetylenes to furnish the Z-acyloxy iodoalkenes. A stereoselective 5-exo-trig Mizoroki-Heck reaction of... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - October 10, 2018 Category: Molecular Biology Authors: Gopinathan Muthusamy Source Type: research