Higher levels of urinary fluoride associated with ADHD in children

(University of Toronto) Higher levels of urinary fluoride during pregnancy are associated with more ADHD-like symptoms in school-age children.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Conclusions: The reviewed articles suggest an association between maternal thyroid function and ADHD, and possibly between early-treated congenital hypothyroidism and ADHD. Study limitations, however, weaken the conclusions in our systematic review, underlining the need for more research. Importantly, there was much variation in the measurement of thyroid hormone function and of ADHD symptoms. Recommendations for future research include using population-based designs, attending to measurement issues for thyroid hormones and ADHD, considering biologically relevant covariates (e.g., iodine intake), and assessing nonlinear ...
Source: Epidemiology - Category: Epidemiology Tags: Perinatal and Child Health Source Type: research
Researchers from the US, including Harvard, looked at 150,000 mothers and babies. Paracetamol use is also linked to a higher risk of ADHD and delayed speech. Experts warn against long-term use.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
This study aimed to investigate the mediating role of parenting behavior in the pathway between maternal postnatal distress and later symptoms of ADHD in the child. Biological mothers living with their children participating in the Longitudinal Study of Australian Children with data available from waves 1 (child age 3–12 months) and 5 (child age 8–9 years) were included in the current study (n = 3456). Postnatal distress was assessed by parent report at wave 1. Parenting warmth, hostility and consistency were assessed by parent report at wave 5. ADHD status at wave 5 was ascertained by p...
Source: European Child and Adolescent Psychiatry - Category: Psychiatry Source Type: research
A new model created by UCLA scientists reveals how the alteration of a specific gene increases the risk for neurodevelopmental problems in mice. When the researchers mutated the gene, it produced symptoms at specific ages in the animal ’s life.Called Glut3, this gene is responsible for moving glucose — the fuel essential to normal function — into brain cells, and plays a crucial role in fetal growth during early pregnancy.Previous studies have linked a GLUT3 mutation in mice to miscarriage and restriction of the fetus ’ growth in the last trimester of pregnancy.“Our findings could lead to new ...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
This study aimed to examine the role of maternal thyroid function during pregnancy on offspring ADHD. A total of 2912 mother-child pairs were included from the Avon Longitudinal Study of Parents and Children. Thyroid parameters were assessed during the first trimester of pregnancy. Offspring ADHD was assessed using the Development and Well-Being Assessment at the ages of 7.5 and 15 years. The odds of presenting with ADHD were estimated using generalized estimating equations. Levels of thyroid-stimulating hormone (odds ratio [OR], 0.92; 95% confidence interval [CI], 0.48–1.75), free thyroxine (OR, 1.07; 95% CI, 0.87&n...
Source: The Journal of Nervous and Mental Disease - Category: Psychiatry Tags: Original Articles Source Type: research
To the Editor I read with interest the article “Association of Exposure to Diethylstilbestrol During Pregnancy With Multigenerational Neurodevelopmental Deficits” by Kioumourtzoglou et al, published inJAMA Pediatrics. Using a valuable cohort of 47 450 women in the Nurses' Health Study II, the authors found that exposure to the potent synthetic estrogen diethylstilbestrol during pregnancy was associated with increased risk of attention-deficit/hyperactivity disorder (ADHD) in the grandchildren. They reasonably conclude that “diethylstilbestrol exposure is associated with multigenerational neurodevelopmenta...
Source: JAMA Pediatrics - Category: Pediatrics Source Type: research
In Reply We appreciate the interest that Drs Ryan and Smith and Dr Costas have expressed in our article. Drs Ryan and Smith raise the issue of exposure misclassification and the potential problem of overreporting of grandmaternal diethylstilbestrol (DES) exposure by mothers whose children have attention-deficit/hyperactivity disorder (ADHD). First, we were not clear in the article, but the κ of 0.74 for nurse and grandmother reporting was specific for DES. We also found that the DES-specific κ value did not vary by ADHD status. Concern for biased recall does need to be considered, and our results should indeed ...
Source: JAMA Pediatrics - Category: Pediatrics Source Type: research
Abstract Conduct disorder is a psychiatric syndrome that most commonly occurs in childhood and adolescence. It is characterized by symptoms of aggression toward people or animals, destruction of property, deceitfulness or theft, and serious violations of rules. Risk factors include male sex, maternal smoking during pregnancy, poverty in childhood, exposure to physical or sexual abuse or domestic violence, and parental substance use disorders or criminal behavior. At least three symptoms should have been present in the past 12 months, with at least one present in the past six months to diagnose conduct disorder. In...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
Journal of Child Psychology and Psychiatry, EarlyView.
Source: Journal of Child Psychology and Psychiatry - Category: Psychiatry Authors: Source Type: research
The objective of the study was to investigate the association between alcohol use during pregnancy and mental disorders in childhood, controlling for confounding risk factors by a longitudinal study of pregnant women and their offspring. The initial cohort comprised pregnant women attending an obstetric service. From the initial sample of 449 pregnant women, 81 mother-child pairs agreed to participate. After 12 years, mother-child pairs were assessed through self-administered questionnaires and semi-structured interviews. The Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Life...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
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