Acinetobacter Infections in Neonates

AbstractPurpose of ReviewMDR-Gram-negative bacteria are a great concern in the neonatal population, with a worldwide rise in the reported incidence and with very limited therapeutic options.Acinetobacter baumannii is responsible for many infections in neonates and outbreaks in neonatal intensive care unit (NICU); also, outbreaks caused by otherAcinetobacter species have been reported. The aim of this review is to document the epidemiology ofAcinetobacter spp. infections in neonates and risk factors for acquisition ofAcinetobacter spp. in the NICU using data from published studies.Recent FindingsAcinetobacter spp. infections are increasing in neonates in NICU. Outbreak caused by multidrug resistant (MDR) or extensively drug resistant (XDR)A. baumannii but also outbreak caused by susceptibleA. soli andA. septicus sp. nov., were reported in neonates.Acinetobacter spp. were responsible for bloodstream infections and respiratory tract infections in neonates. Risk factors forA. baumannii acquisition in neonates were low birthweight, length of NICU stay, umbilical catheterization, central-venous catheterization, assisted ventilation, and prior antibiotic use.SummaryThis review highlights the importance of surveillance of risk factors for healthcare-associated infections in NICU to control MDR and XDRA. baumannii infections in neonates.
Source: Current Infectious Disease Reports - Category: Infectious Diseases Source Type: research