3 More Kids Have Developed a Rare, Polio-Like Illness —and Health Officials Don’t Know Why

Three more children have come down with a polio-like nervous system disorder that can cause paralysis, fueling an ongoing investigation into an outbreak of the rare disease. Three children are being treated for suspected cases of acute flaccid myelitis (AFM) at UPMC Children’s Hospital of Pittsburgh, ABC News reports. The new patients join a cluster of cases in Minnesota and another in Colorado. As of September 30, the Centers for Disease Control and Prevention (CDC) had this year recorded 38 confirmed cases of the severe condition, which typically affects kids and can result in muscle weakness or paralysis, respiratory failure and even death. The Minnesota Department of Health (MDH) has since mid-September received a half-dozen reports of children with AFM, according to a statement. All of the Minnesota patients are younger than 10, and cases have been reported in northeastern and central parts of the state, as well as the Twin Cities area. “That is definitely more than would be expected,” says Kris Ehresmann, director of the infectious disease division at MDH. “To have six cases is really a striking departure from the norm.” Indeed, AFM is exceedingly rare: The CDC estimates that fewer than one in a million people in the U.S. get it each year, though it has been on the rise since a 2014 outbreak, sparking a CDC investigation. Minnesota typically sees a case or less per year, according to the MDH statement; even in 2014, only three cases were r...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime Minnesota onetime Source Type: news

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Publication date: Available online 18 May 2019Source: Protein Expression and PurificationAuthor(s): Josselin Corzo-Gómez, Julio García Cordero, Alfredo E. Montes Gómez, Karen Bernal Siria, Karime Namorado-Tónix, Benito Gutiérrez Castañeda, Leticia Cedillo-BarrónAbstractThe envelope (E) protein from Dengue and Zika viruses comprises three functional and structural domains (DI, DII, and DIII). Domain III induces most of the neutralizing antibodies and, as such, is considered as having the highest antigenic potential for the evaluation of population-level surveillance and for d...
Source: Protein Expression and Purification - Category: Biochemistry Source Type: research
Authors: Mayser P Abstract In a preschool a long-lasting outbreak of Trichophyton (T.) tonsurans tinea capitis was stopped by a concurrent screening of all persons at-risk (N = 264) with the hairbrush technique and a therapy based on clinical picture as well as on the quantitative results of the culture. In addition to the 5 symptomatic patients 10 asymptomatic carriers undetected until now were especially important as vectors. With the rising incidence of T. tonsurans and T. violaceum and the return of Microsporum (M.) audouinii in central Europe such outb...
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
Vincent travels to the European Congress of Virology in Rotterdam and with local co-host Marion Koopmans speak with Martin Beer, Stephan Gunther, and Vera Ross about their careers and their work on Lassa virus, Borna virus, and insect viruses. Click arrow to play Download TWiV 548 (43 MB .mp3, 72 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show […]
Source: virology blog - Category: Virology Authors: Tags: This Week in Virology baculovirus Borna virus encaphalitis European Congress of Virology Lassa virus metagenomics nigeria outbreak response transplant recipient viral virus behavior modification viruses zombie caterpillar Source Type: blogs
Publication date: Available online 18 May 2019Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Kahina Kali, Moustafa Kardjadj, Nacera Touaghit, Fatma Yahiaoui, Meriem Hind Ben-MahdiAbstractSheep pox is a disease of veterinary concern to small ruminant producers and veterinary diagnosticians, because of the associated tangible economic losses. The epidemiological analysis of sheep pox, among vaccinated sheep flock in Algeria from 2007 to 2016, showed that the disease outbreaks occurred every year and across all Algeria region with an average of 44.9 outbreaks per year, these outbreaks correlate...
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
Publication date: Available online 18 May 2019Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Fuxiao Liu, Hongliang Zhang, Wenhua LiuAbstractGoatpox (GTP), sheeppox (SPP) and lumpy skin disease (LSD) are three severe diseases of goat, sheep and cattle. Their typical clinical symptoms are characterized by vesicles, papules, nodules, pustules and scabs on animal skins. The GTP, SPP and LSD are caused by goatpox virus (GTPV), sheeppox virus (SPPV) and lumpy skin disease virus (LSDV), respectively, all of which belong to the genus Capripoxvirus in the family Poxviridae. Several capripoxvirus (CaP...
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
Londoner Sarah Westcott, 44, right, had her youngest son Gabriel, now three, immunised after her 14-year-old daughter Bridy, left, suffered badly with chickenpox as a young girl.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
The objective of this study was to determine the epidemiological characteristics of leptospirosis in pets and in humans in peridomestic settings in Nicaragua between 2014 and 2016. Methods: The samples were taken in areas where cases were confirmed in humans using non-probabilistic sampling in 10 of the country's 17 departments. This included 112 urine samples from pets, 129 water samples, and 69 soil samples in order to isolate leptospires in Ellinghausen-McCullough-Johnson-Harris (EMJH) medium. Furthermore, the microscopic agglutination test (MAT) was applied to 263 samples of animal serum, and 88 isolates were analy...
Source: Pan American Journal of Public Health - Category: International Medicine & Public Health Tags: Rev Panam Salud Publica Source Type: research
Conclusion: The VAE-RS is useful to monitor immunization safety. However, municipal services must increase adherence to the system and perform the required investigation and reporting of VAE, with timely and adequate completion of the VAE-RS form. Knowledge regarding VAE can be used in the daily routine of surveillance services, improving the safety of immunobiological agents. PMID: 31093041 [PubMed]
Source: Pan American Journal of Public Health - Category: International Medicine & Public Health Tags: Rev Panam Salud Publica Source Type: research
Conclusions: No high-quality data were found on cost-effectiveness of interventions on TB diagnostics/screening, treatment, or prevention in homeless people. However, active searching for cases via mobile screening, and financial incentives, could help increase treatment adherence, and the use of IGRA helps boost detection. TB in homeless people is neglected worldwide, especially in developing countries, where this disease tends to afflict more people made vulnerable by their precarious living conditions. Public funding mechanisms should be created to develop cross-sectoral actions targeting homeless people, as the complex...
Source: Pan American Journal of Public Health - Category: International Medicine & Public Health Tags: Rev Panam Salud Publica Source Type: research
The Centers for Disease Control and Prevention (CDC) has so far this year recorded 127 suspected cases of a polio-like nervous system disorder that can cause paralysis, fueling an ongoing investigation into an outbreak of the rare disease. Of those 127 illnesses, 62 cases in 22 states are confirmed to be acute flaccid myelitis (AFM), the CDC said Tuesday. The CDC recorded only 33 confirmed cases of the severe condition — which typically affects kids and can result in muscle weakness or paralysis, respiratory failure and even death — during all of last year, though there were 149 cases the year before. “W...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime Minnesota onetime Source Type: news
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