3 More Kids Have Developed a Rare, Polio-Like Illness —and Health Officials Don’t Know Why

Three more children have come down with a polio-like nervous system disorder that can cause paralysis, fueling an ongoing investigation into an outbreak of the rare disease. Three children are being treated for suspected cases of acute flaccid myelitis (AFM) at UPMC Children’s Hospital of Pittsburgh, ABC News reports. The new patients join a cluster of cases in Minnesota and another in Colorado. As of September 30, the Centers for Disease Control and Prevention (CDC) had this year recorded 38 confirmed cases of the severe condition, which typically affects kids and can result in muscle weakness or paralysis, respiratory failure and even death. The Minnesota Department of Health (MDH) has since mid-September received a half-dozen reports of children with AFM, according to a statement. All of the Minnesota patients are younger than 10, and cases have been reported in northeastern and central parts of the state, as well as the Twin Cities area. “That is definitely more than would be expected,” says Kris Ehresmann, director of the infectious disease division at MDH. “To have six cases is really a striking departure from the norm.” Indeed, AFM is exceedingly rare: The CDC estimates that fewer than one in a million people in the U.S. get it each year, though it has been on the rise since a 2014 outbreak, sparking a CDC investigation. Minnesota typically sees a case or less per year, according to the MDH statement; even in 2014, only three cases were r...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime Minnesota onetime Source Type: news

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Publication date: February 2019Source: Biomedicine &Pharmacotherapy, Volume 110Author(s): Sanam Nami, Ali Aghebati-Maleki, Hamid Morovati, Leili Aghebati-MalekiAbstractInvasive candidiasis (IC) can affect individuals with various underlying diseases hospitalized in different parts of hospitals. In recent decades, IC has caused 27–55% mortality in general population. Although Candida albicans (C. albicans) is still the most common cause of IC, non-albicans infections such as C. krusei, C. glabrata, C. lusitaniae, C. tropicalis, and C. parapsilosis have been increased in recent years. Treatment of invasive fungal i...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
ConclusionCVID and IgG deficiency do not share the same disease spectrum, the former being associated with immunodysregulative manifestations and markers of a more severe immune defect. These data may allow clinicians to distinguish these conditions and the management differences that these patients pose.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Authors: Göktuğ Kadıoğlu B, Çınar Tanrıverdi E, Alay H, Uçar M Abstract Cervical cancer is a common female cancer that could be diagnosed early with screening methods. Almost all cases are caused by human papilloma virus (HPV) infection. Therefore, detecting the presence of HPV DNA is important for early diagnosis and treatment. Regular determination of screening tests enables early detection of patients with the risk of cervical cancer. For this purpose, since August 2014 a new screening program has been carried out by Early Diagnosis, Screening and Training of Cancer Centers (KETEM). The a...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
This study reports an investigation of the determinants of the likelihood consumers will revisit a restaurant that has had a foodborne illness outbreak, including the moderating effects of restaurant type and consumer dining frequency. A scenario-based survey was distributed via Amazon's Mechanical Turk to collect data from 1034 respondents; the tally of valid responses was 1025. Partial least squares-based structural equation modeling (PLS-SEM) showed perceived vulnerability and perceived severity to be statistically significant; both also negatively affected customer intentions to patronize restaurants cited for serving ...
Source: Food Control - Category: Food Science Source Type: research
(MedPage Today) -- This week's topics also include prostatectomy versus watchful waiting, and flu vaccines and heart failure
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news
This study validates the proof of concept that the endonuclease domain of Arenavirus can be used as a target for anti-arena-viral drug discovery and that both diketo acids and N-hydroxyisoquinoline-1,3-diones can be considered further as potential metal-chelating pharmacophores.
Source: Antiviral Therapy - Category: Virology Source Type: research
This study used experiences of attending four PPR vaccination campaigns in Ethiopia to estimate various cost components in pastoral and mixed-crop livestock systems. These components included: cost of vaccine; vaccine transport from the producer to the local storage facility; storage of vaccine at the local facility; delivery and administration of vaccine in the field; opportunity cost of farmer’s time to attend the vaccination; co-ordination of vaccination campaign; publicity and mobilisation costs; vaccine wastage from missed shots and vaccine discard. The overall cost of vaccination was approximately 6 Ethiopian b...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
Authors: González-Sánchez JA, Ramírez-Arroyo GF Abstract Chikungunya fever (CHIKF) is a re-emerging mosquito-borne disease caused by a virus endemic to Africa and Asia. Due to the ease with which its vectors propagate, the virus has spread to India and Europe, and more recently it arrived to the Caribbean, eventually extending into North, Central, and South America. According to the World Health Organization (WHO), the most common clinical manifestations are abrupt fever, polyarthralgia, headache, maculopapular rash, myalgia, and nausea/vomiting. Severe joint pain and stiffness have been known ...
Source: Puerto Rico Health Sciences Journal - Category: International Medicine & Public Health Tags: P R Health Sci J Source Type: research
Abstract Nearly 1 million people become infected every day with any of the four major curable sexually transmitted infections (STIs), namely trichomoniasis, chlamydia, gonorrhea, and syphilis. Despite huge global incidence, STIs remain as neglected diseases. The success of antiretrovirals for halting progression to AIDS in HIV-infected individuals and for stopping HIV transmission to uninfected contacts, either as pre- or post-exposure -prophylaxis, has to lead to increased risky sexual behaviors through risk compensation. Recent epidemics and outbreaks of STIs among men having sex with men reflect the global loss...
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
Publication date: 21 February 2019Source: Journal of Theoretical Biology, Volume 463Author(s): Jie Jiang, Anglu Shen, Hao Wang, Sanling YuanAbstractPhosphorus is an essential element for the growth and reproduction of algae. In recent years, the frequent outbreaks of algal blooms caused by eutrophication have drawn much attention to the influence of phosphate (P) uptake on the growth of algal cells. The previous study only considered the effect of total P pools on the P uptake process of algal cells and considered the process as one stage, which is insufficient. P uptake by algae is actually a two-stage kinetic process bec...
Source: Journal of Theoretical Biology - Category: Biology Source Type: research
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