Dementia test: Alzheimer’s could be spotted five years before symptoms appear using this

DEMENTIA signs and symptoms can be difficult to spot because the disease can affect people differently. But scientists have created an AI which they claim can spot Alzheimer ’s before symptoms appear. 
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: de Castro AA, Soares FV, Pereira AF, Polisel DA, Caetano MS, Leal DHS, da Cunha EFF, Nepovimova E, Kuca K, Ramalho TC Abstract INTRODUCTION: Alzheimer's disease (AD) is the most common cause of dementia. Clinical progress in this pathogenesis field has drawn the attention of researchers, stimulating the investigation of novel treatment methods. Current therapies that deal with cholinesterase inhibitors and/or NMDA antagonists have shown a modest symptomatic potential, increasing the need for research into more efficient therapeutics. The goal of this review is to summarize the advances in, and the potential o...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
Publication date: Available online 19 April 2019Source: Alzheimer's &DementiaAuthor(s): Michel Goedert
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
FRIDAY, April 19, 2019 -- Alzheimer's and dementia are not an inevitable part of normal aging, and a little exercise might help keep them at bay, a new study suggests. The researchers found that every hour of light exercise on top of recommended...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
While Alzheimer’s disease will progress differently for each person, scientists and clinicians have attempted to stage the disease as a way that helps people living with Alzheimer’s and their families understand what is happening, as well as to plan for the future. Some divide AD into seven stages, some five stages, but currently, three stages is the format most often used. The Alzheimer’s Association uses three stages, so that is what we will use for our foundation here. View the slideshow on HealthCentral about how the caregiver's role can evolve as the stages of Alzheimer's advance: Carol Bra...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
Pathological aggregation of the transactive response DNA-binding protein of 43 kDa (TDP-43) is associated with several neurodegenerative disorders, including ALS, frontotemporal dementia, chronic traumatic encephalopathy, and Alzheimer's disease. TDP-43 aggregation appears to be largely driven by its low-complexity domain (LCD), which also has a high propensity to undergo liquid–liquid phase separation (LLPS). However, the mechanism of TDP-43 LCD pathological aggregation and, most importantly, the relationship between the aggregation process and LLPS remains largely unknown. Here, we show that amyloid formation by th...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Protein Structure and Folding Source Type: research
DEMENTIA causes a wide range of symptoms, which tend to worsen as the disease progresses, but spotting the signs early can allow you to get the right help and treatment to keep the condition under control for as long as possible. There is one main early symptom of Alzheimer ’s disease - the most common type of dementia - everyone should be aware of.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Abstract AIM: To determine the association between dementia and age-related macular degeneration (AMD) using meta-analysis. METHODS: We searched in the MEDLINE, EMBASE, Web of Knowledge, PsycInfo and Cochrane database of systematic reviews for studies published from March 1959 to March 2018. We included cross-sectional, case-control and cohort studies that evaluated the association of dementia/Alzheimer's disease (AD) with AMD (as outcome) and the association of AMD with dementia/AD (as outcome). Studies that compared cognitive functions between AMD and controls were also included. The summary outcomes, namel...
Source: The British Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Br J Ophthalmol Source Type: research
Grand Total EEG Score Can Differentiate Parkinson's Disease From Parkinson-Related Disorders Ela Austria Barcelon1,2*, Takahiko Mukaino1, Jun Yokoyama1, Taira Uehara2, Katsuya Ogata2, Jun-ichi Kira1 and Shozo Tobimatsu2 1Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan2Department of Clinical Neurophysiology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Background: Semi-quantitative electroencephalogram (EEG) analysis is easy to perform and has been used to differentiate dementias, as well ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Late-life depression is one of the most common mental illnesses in the aging population and its prevalence is exacerbated in those with dementia.1 Onset of depressive symptoms in late-life is precipitated by risk factors including cerebrovascular disease, old age, vulnerable genotypes, low socioeconomic status and stressful life events.2-4 Of these risks, the most studied has been cerebrovascular disease, which has been proposed by the vascular depression hypothesis to predispose, precipitate and perpetuate late-life depression by altering cerebral white matter.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Regular Research Article Source Type: research
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