Germline Mutations in ATM and BRCA1/2 Are Associated with Grade Reclassification in Men on Active Surveillance for Prostate Cancer

ConclusionsMutation status of BRCA1/2 and ATM is associated with GR among men undergoing AS.Patient summaryMen on active surveillance with inherited mutations in BRCA1/2 and ATM are more likely to harbor aggressive prostate cancer.
Source: European Urology - Category: Urology & Nephrology Source Type: research