Pets Need Not Derail Asthma Control in Kids

(MedPage Today) -- Following NAEPP treatment guidelines improved control in 3-year study
Source: MedPage Today Pulmonary - Category: Respiratory Medicine Source Type: news

Related Links:

Authors: Lee E, Hong SJ Abstract Allergic disease, including allergic rhinitis, asthma, and atopic dermatitis, are huge heterogeneous diseases, encompassing diverse phenotypes with different pathogenesis. Phenotype studies on allergic diseases are important in that they can facilitate the identification of risk factors and the underlying pathophysiologies, resulting in the application of more effective treatment, selection of better response to the treatment, and prediction of prognosis for each phenotype. In the early phase of phenotype studies in allergic diseases, artificial classifications were usually performe...
Source: Korean Journal of Pediatrics - Category: Pediatrics Tags: Korean J Pediatr Source Type: research
(NIH/National Heart, Lung and Blood Institute) A study of nearly 300 patients with mild persistent asthma found that inhaled steroids -- long considered the gold standard for asthma treatment -- were no more effective than placebo in nearly three-fourths of the study patients, all over age 12. Inhaled steroids were better than placebo for a subset of the patients who had high levels of a particular type of inflammatory cells, called eosinophils, in their sputum, but they represented about a fourth of patients enrolled in the trial.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
ConclusionsPrompt epinephrine treatment is crucial. Use of antihistamines in conjunction with epinephrine may reduce the risk of uncontrolled reactions (administration of 2 or more doses of epinephrine in the ED), although our findings do not support the use of corticosteroids.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: August 2019Source: Biochemical Systematics and Ecology, Volume 85Author(s): Antônio Q. da Silva Júnior, Diana S. da Silva, Pablo Luis B. Figueiredo, Sandra Layse F. Sarrazin, Leoneide Erica M. Bouillet, Ricardo B. de Oliveira, José Guilherme S. Maia, Rosa Helena V. MourãoAbstractIn Brazil, the infusion from leaves of Lippia alba (Verbenaceae), popularly known as Erva-cidreira, is used for the treatment of infections, digestive disorders, cough, asthma, colds and anxiolytic, among others. It has been used in phytotherapy practices of communities of Santarém, Pará St...
Source: Biochemical Systematics and Ecology - Category: Biochemistry Source Type: research
AbstractJay Asher ’s novelThirteen Reasons Why and its Netflix adaptation have enjoyed widespread popularity. While they draw needed attention to issues like bullying and teen estrangement, they may have an unintended effect: they mislead about the etiology of suicide and even glamorize it to a degree. The medical literature has shown that suicide is almost always the result of psychiatric disorder, not provocative stress, in much the same way an asthmatic crisis is primarily the result of an underlying medical condition, not an allergic stimulus. Both the novel and Netflix series ignore this premise and even belittl...
Source: Journal of Medical Humanities - Category: Medical Ethics Source Type: research
AbstractThe aim of this study is to investigate the potential roles of miR-943-3p and its target gene secreted frizzled-related proteins4 (SFRP4) in allergic asthma and elucidate its underlying mechanism, which may prompt a new clue about developing novel treatments of this disease. An allergic asthma mouse model was generated by challenging with ovalbumin (OVA); lung pathological features of mice were viewed using H&E staining; thickness of subepithelial fibrosis and smooth muscle was measured using Masson ’s trichrome staining. Inflammatory cells from bronchoalveolar lavage fluid (BALF) were counted based on Diff-Q...
Source: Cell and Tissue Research - Category: Cytology Source Type: research
Many epidemiological studies have reported a positive association between prenatal exposure to paracetamol and childhood wheezing and asthma. We investigated whether the link between prenatal analgesic exposure and asthma/wheeze is specific to paracetamol, and whether it is causal or confounded. Using linked Swedish health register data we investigated the relation between various prescribed analgesics in pregnancy and the risk of childhood asthma/wheeze in a population of 492 999, and used negative paternal control and sibling comparison approaches to explore unmeasured confounding. After controlling for potential confoun...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Asthma Source Type: research
Adherence to inhaled maintenance therapy in severe asthma is rarely adequately assessed, and its influence on trial outcomes is unknown. We systematically determined how adherence to maintenance therapy is assessed in clinical trials of "add-on" therapy for severe asthma. We model the improvement in trial power that could be achieved by accurately assessing adherence. A systematic search of six major databases identified randomised trials of add-on therapy for severe asthma. The relationship between measuring adherence and study outcomes was assessed. An estimate of potential improvements in statistical power and...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Asthma Source Type: research
Early allergic sensitisation (atopy) is the first step in the development of allergic diseases such as atopic asthma later in life. Genes and pathways associated with atopy and atopic asthma in children and adolescents have not been well characterised. A transcriptome-wide association study (TWAS) of atopy and atopic asthma in white blood cells (WBCs) or whole blood was conducted in a cohort of 460 Puerto Ricans aged 9–20 years (EVA-PR study) and in a cohort of 250 Swedish adolescents (BAMSE study). Pathway enrichment and network analyses were conducted to further assess top findings, and classification models o...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Asthma Source Type: research
Asthma is the most common long-term respiratory condition, affecting more than 300 million people worldwide and, despite concerted efforts to achieve disease control and reduce exacerbations, it claims approximately 1000 lives each day [1]. The health and financial burdens associated with asthma are increasing, both at individual and population levels. A recent study estimated the annual cost of asthma in the USA to be more than USD 80 billion, taking into account direct medical costs, mortality and loss of attendance at school and work [2].
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Editorials Source Type: research
More News: Asthma | Children | Respiratory Medicine | Study