Effectiveness of standard fasting guidelines as assessed by gastric ultrasound examination: A clinical audit

Conclusion: In our audit, we found that risk factor association has a greater effect on residual gastric volume than hours of fasting. While the current fasting guidelines are adequate for healthy individuals, they are not conclusive in patients with risk factors. Ultrasound assessment of preoperative gastric volume is an effective screening tool in patients with risk factors.
Source: Indian Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research

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Publication date: March 2019Source: LWT, Volume 102Author(s): Tanya L. Swer, Komal ChauhanAbstractPrunus nepalensis L. (Sohiong) is an important indigenous fruit crop in Meghalaya (India). The purple coloured fruit has high anthocyanin content which can be tapped for its colouring attributes and therapeutic benefits. Physicochemical characteristics, thermal and storage stability analysis of freeze dried extracts obtained by enzyme assisted extraction (EAE) and conventional solvent extraction (CSE) from P. nepalensis L. were investigated. The physicochemical characteristics, viz. colour (L, a, b and ΔE) and hygroscopi...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
Publication date: Available online 16 December 2018Source: Redox BiologyAuthor(s): Mateusz A. Stochelski, Tomasz Wilmanski, Mitchell Walters, John R. BurgessAbstractDiabetes mellitus is one of the most common chronic diseases in the United States and peripheral neuropathy (PN) affects at least 50% of diabetic patients. Medications available for patients ameliorate symptoms (pain), but do not protect against cellular damage and come with severe side effects, leading to discontinued use. Our research group uses differentiated SH-SY5Y cells treated with advanced glycation end products (AGE) as a model to mimic diabetic condit...
Source: Redox Biology - Category: Biology Source Type: research
Authors: Harsch IA, Kaestner RH, Konturek PC Abstract Insulinotropic oral antidiabetics (OAD) such as sulfonylureas and (SU) glinides are among the frequently prescribed OAD. Side effects are the potential to induce hypoglycemias and weight gain. The aim was to assess the self-managing skills in case of a hypoglycemic event in an elderly type 2 diabetic patient population. In a 2-year period, 160 hospitalized patients (mean age 77.4 years) under insulinotrophic OAD were interviewed using a standardized questionnaire. Additionally, possible dementia was evaluated by using the Mini-Mental State Examination (MMSE) and...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Authors: Mysliwiec P, Choromanska B, Winnicka MM, Kaminski K, Mysliwiec H, Dadan J, Supruniuk E, Chabowski A Abstract Chronic inflammation is a critical feature of obesity in the development of myocardial dysfunction. The observations that interleukin-6 (IL-6) is implicated in lipid and glucose homeostasis as well as its connection with the pathogenesis of insulin resistance might suggest the involvement of this cytokine in metabolic disorders of the failing heart. In the present study we aimed to assess the effects of IL-6 ablation in mice fed with normal and high fat diet on the myocardial expression of glucose a...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Authors: Karczewski J, Śledzińska E, Baturo A, Jończyk I, Maleszko A, Maleszko A, Samborski P, Begier-Krasińska B, Dobrowolska A Abstract The prevalence of obesity has recently increased dramatically and has contributed to the increasing prevalence of various pathological conditions, including type 2 diabetes mellitus, nonalcoholic fatty liver disease, asthma, various types of cancer, cardiovascular and neurodegenerative diseases, and others. Accumulating evidence points to localized inflammation in adipose tissue, which, in turn, promotes systemic low-grade inflammation as a primary force contributing to the d...
Source: European Cytokine Network - Category: Molecular Biology Tags: Eur Cytokine Netw Source Type: research
In conclusion, inflammatory cytokines and adipokines seem to have a pivotal role in the regulation of spermatogenesis; any imbalance in this stable environment may lead to infertility. Nevertheless, further studies are needed to clarify their exact role. PMID: 30547889 [PubMed - in process]
Source: European Cytokine Network - Category: Molecular Biology Tags: Eur Cytokine Netw Source Type: research
Authors: Bastard JP, Fellahi S, Audureau É, Layese R, Roudot-Thoraval F, Cagnot C, Mahuas-Bourcier V, Sutton A, Ziol M, Capeau J, Nahon P Abstract An obesity-related altered adipose tissue secretion is suggested as a risk factor for hepatocellular carcinoma (HCC) in patients with hepatitis C virus (HCV) cirrhosis. However, no prospective study has yet examined the predictive value of circulating adipokines and immuno-inflammatory biomarkers regarding this risk. This was a case-control study nested in a prospective French national cohort of HCV-infected patients with biopsy-proven compensated cirrhosis. We se...
Source: European Cytokine Network - Category: Molecular Biology Tags: Eur Cytokine Netw Source Type: research
Publication date: 15 December 2018Source: New Scientist, Volume 240, Issue 3208Author(s): Edd Gent
Source: New Scientist - Category: Science Source Type: research
CONCLUSIONS: The data of this post-marketing study meet the request by the French authorities for additional data on conditions of use in everyday practice. They confirmed the tolerance and long-term effect of capsaicin 8% patch in patients with peripheral neuropathic pain in real-world conditions. PMID: 30550354 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
CONCLUSION: Uncapping the iGlar dose in LixiLan-O and LixiLan-L would not have led to significant improvements in mean A1C reduction in the iGlar arm, supporting the conclusion that iGlarLixi provides additional, clinically-relevant glycemic control versus iGlar alone. PMID: 30550345 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
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