TBS as a Tool to Differentiate the Impact of Antiresorptives onCortical and Trabecular Bone in Children With OsteogenesisImperfecta
Introduction/Background: Osteogenesis imperfecta is a hereditary connective tissue disorder, resulting in low bone mass and high bone fragility. Dual-energy X-ray absorptiometry (DXA) and in adulthood also the trabecular bone score (TBS) are well established to assess bone health and fracture risk. The purpose of this investigation was to assess the usefulness of TBS in respect to different treatment regimes in children with osteogenesis imperfecta. Changes of areal bone mineral density (aBMD) and TBS using DXA scans of children treated with antiresorptive therapies were evaluated.
Source: Journal of Clinical Densitometry - Category: Radiology Authors: Mirko Rehberg, Renaud Winzenrieth, Heike Hoyer-Kuhn, Ibrahim Duran, Eckhard Schoenau, Oliver Semler Source Type: research
More News: Children | DEXA Scan | Orthopaedics | Osteogenesis Imperfecta (brittle bone disease) | PET Scan | Radiology